eF-site ID 3kuk-AB PDB Code 3kuk Chain A, B click to enlarge Title Trapping of an oxocarbenium ion intermediate in UP crystals Classification TRANSFERASE Compound Uridine phosphorylase Source Bos taurus (Bovine) (A5PJH9_BOVIN) Sequence A:  DLVQLCNPHIAAMKEDILYHFSLSTSTHDFPAMFGDVKFV CVGGSPSRMKAFIKYVAMELGFAADYPNICEGTDRYAMFK VGPVLSVSHGMGVPSIAIMLHELIKLLYHAHCSGVTLIRI GTSGGIGLEPGSVVITRQAVDPCFKPEFEQIVLGKREVRN TDLDEQLVQELARCSAELGEFPTVVGNTMCTLDFYEGQGR LDGALCSYTEKDKQDYLRAAYAAGIRNIEMEASVFAAMCN ACGLRAAVVCVTLLNRLEGDQISSPHDVLAEYQQRPQRLV GQFIKKRLMQ B:  HNDLVQLCNPHIAAMKEDILYHFSLSTSTHDFPAMFGDVK FVCVGGSPSRMKAFIKYVAMELGFAHADYPNICEGTDRYA MFKVGPVLSVSHGMGVPSIAIMLHELIKLLYHAHCSGVTL IRIGTSGGIGLEPGSVVITRQAVDPCFKPEFEQIVLGKRE VRNTDLDEQLVQELARCSAELGEFPTVVGNTMCTLDFYEG QGRLDGALCSYTEKDKQDYLRAAYAAGIRNIEMEASVFAA MCNACGLRAAVVCVTLLNRLEGDQISSPHDVLAEYQQRPQ RLVGQFIKKRLMQ Description Functional site 1) chain A residue 59 type sequence G description BINDING SITE FOR RESIDUE SO4 A 310 source : AC1 2) chain A residue 137 type sequence R description BINDING SITE FOR RESIDUE SO4 A 310 source : AC1 3) chain A residue 139 type sequence G description BINDING SITE FOR RESIDUE SO4 A 310 source : AC1 4) chain A residue 140 type sequence T description BINDING SITE FOR RESIDUE SO4 A 310 source : AC1 5) chain B residue 93 type sequence R description BINDING SITE FOR RESIDUE SO4 A 310 source : AC1 6) chain A residue 109 type sequence M description BINDING SITE FOR RESIDUE DUR A 311 source : AC2 7) chain A residue 140 type sequence T description BINDING SITE FOR RESIDUE DUR A 311 source : AC2 8) chain A residue 141 type sequence S description BINDING SITE FOR RESIDUE DUR A 311 source : AC2 9) chain A residue 142 type sequence G description BINDING SITE FOR RESIDUE DUR A 311 source : AC2 10) chain A residue 212 type sequence F description BINDING SITE FOR RESIDUE DUR A 311 source : AC2 11) chain A residue 216 type sequence Q description BINDING SITE FOR RESIDUE DUR A 311 source : AC2 12) chain A residue 218 type sequence R description BINDING SITE FOR RESIDUE DUR A 311 source : AC2 13) chain A residue 246 type sequence I description BINDING SITE FOR RESIDUE DUR A 311 source : AC2 14) chain A residue 247 type sequence E description BINDING SITE FOR RESIDUE DUR A 311 source : AC2 15) chain A residue 249 type sequence E description BINDING SITE FOR RESIDUE DUR A 311 source : AC2 16) chain B residue 35 type sequence H description BINDING SITE FOR RESIDUE DUR A 311 source : AC2 17) chain A residue 93 type sequence R description BINDING SITE FOR RESIDUE SO4 B 310 source : AC3 18) chain B residue 59 type sequence G description BINDING SITE FOR RESIDUE SO4 B 310 source : AC3 19) chain B residue 63 type sequence R description BINDING SITE FOR RESIDUE SO4 B 310 source : AC3 20) chain B residue 137 type sequence R description BINDING SITE FOR RESIDUE SO4 B 310 source : AC3 21) chain B residue 139 type sequence G description BINDING SITE FOR RESIDUE SO4 B 310 source : AC3 22) chain B residue 140 type sequence T description BINDING SITE FOR RESIDUE SO4 B 310 source : AC3 23) chain A residue 34 type sequence Y description BINDING SITE FOR RESIDUE DUR B 311 source : AC4 24) chain A residue 35 type sequence H description BINDING SITE FOR RESIDUE DUR B 311 source : AC4 25) chain A residue 93 type sequence R description BINDING SITE FOR RESIDUE DUR B 311 source : AC4 26) chain B residue 109 type sequence M description BINDING SITE FOR RESIDUE DUR B 311 source : AC4 27) chain B residue 140 type sequence T description BINDING SITE FOR RESIDUE DUR B 311 source : AC4 28) chain B residue 141 type sequence S description BINDING SITE FOR RESIDUE DUR B 311 source : AC4 29) chain B residue 142 type sequence G description BINDING SITE FOR RESIDUE DUR B 311 source : AC4 30) chain B residue 212 type sequence F description BINDING SITE FOR RESIDUE DUR B 311 source : AC4 31) chain B residue 216 type sequence Q description BINDING SITE FOR RESIDUE DUR B 311 source : AC4 32) chain B residue 218 type sequence R description BINDING SITE FOR RESIDUE DUR B 311 source : AC4 33) chain B residue 246 type sequence I description BINDING SITE FOR RESIDUE DUR B 311 source : AC4 34) chain B residue 247 type sequence E description BINDING SITE FOR RESIDUE DUR B 311 source : AC4 35) chain B residue 248 type sequence M description BINDING SITE FOR RESIDUE DUR B 311 source : AC4 36) chain B residue 249 type sequence E description BINDING SITE FOR RESIDUE DUR B 311 source : AC4 37) chain A residue 106-121 type prosite sequence SHGMGVPSIAIMLHEL description PNP_UDP_1 Purine and other phosphorylases family 1 signature. ShGMGvPSiAImlhEL source prosite : PS01232

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