eF-site ID 3ku4-ABCD PDB Code 3ku4 Chain A, B, C, D click to enlarge Title Trapping of an oxocarbenium ion intermediate in UP crystals Classification TRANSFERASE Compound Uridine phosphorylase Source Bos taurus (Bovine) (A5PJH9_BOVIN) Sequence A:  NDLVQLCNPHIAAMKEDILYHFSLSTSTHDFPAMFGDVKF VCVGGSPSRMKAFIKYVAMELGFAHPDYPNICEGTDRYAM FKVGPVLSVSHGMGVPSIAIMLHELIKLLYHAHCSGVTLI RIGTSGGIGLEPGSVVITRQAVDPCFKPEFEQIVLGKREV RNTDLDEQLVQELARCSAELGEFPTVVGNTMCTLDFYEGQ GRLDGALCSYTEKDKQDYLRAAYAAGIRNIEMEASVFAAM CNACGLRAAVVCVTLLNRLEGDQISSPHDVLAEYQQRPQR LVGQFIKKRLM B:  NDLVQLCNPHIAAMKEDILYHFSLSTSTHDFPAMFGDVKF VCVGGSPSRMKAFIKYVAMELGFAHPGADYPNICEGTDRY AMFKVGPVLSVSHGMGVPSIAIMLHELIKLLYHAHCSGVT LIRIGTSGGIGLEPGSVVITRQAVDPCFKPEFEQIVLGKR EVRNTDLDEQLVQELARCSAELGEFPTVVGNTMCTLDFYE GQGRLDGALCSYTEKDKQDYLRAAYAAGIRNIEMEASVFA AMCNACGLRAAVVCVTLLNRLEGDQISSPHDVLAEYQQRP QRLVGQFIKKRLM C:  DLVQLCNPHIAAMKEDILYHFSLSTSTHDFPAMFGDVKFV CVGGSPSRMKAFIKYVAMELGFADYPNICEGTDYAMFKVG PVLSVSHGMGVPSIAIMLHELIKLLYHAHCSGVTLIRIGT SGGIGLEPGSVVITRQAVDPCFKPEFEQIVLGKREVRNTD LDEQLVQELARCSAELGEFPTVVGNTMCTLDFYEGQGRLD GALCSYTEKDKQDYLRAAYAAGIRNIEMEASVFAAMCNAC GLRAAVVCVTLLNRLEGDQISSPHDVLAEYQQRPQRLVGQ FIKKRLM D:  LVQLCNPHIAAMKEDILYHFSLSTSTHDFPAMFGDVKFVC VGGSPSRMKAFIKYVAMELGFADYPNICEGTDRYAMFKVG PVLSVSHGMGVPSIAIMLHELIKLLYHAHCSGVTLIRIGT SGGIGLEPGSVVITRQAVDPCFKPEFEQIVLGKREVRNTD LDEQLVQELARCSAELGEFPTVVGNTMCTLDFYEGQGRLD GALCSYTEKDKQDYLRAAYAAGIRNIEMEASVFAAMCNAC GLRAAVVCVTLLNRLEGDQISSPHDVLAEYQQRPQRLVGQ FIKKRLM Description Functional site 1) chain A residue 60 type sequence S description BINDING SITE FOR RESIDUE SO4 A 310 source : AC1 2) chain A residue 63 type sequence R description BINDING SITE FOR RESIDUE SO4 A 310 source : AC1 3) chain B residue 59 type sequence G description BINDING SITE FOR RESIDUE SO4 B 310 source : AC2 4) chain B residue 60 type sequence S description BINDING SITE FOR RESIDUE SO4 B 310 source : AC2 5) chain B residue 63 type sequence R description BINDING SITE FOR RESIDUE SO4 B 310 source : AC2 6) chain C residue 59 type sequence G description BINDING SITE FOR RESIDUE SO4 C 310 source : AC3 7) chain C residue 60 type sequence S description BINDING SITE FOR RESIDUE SO4 C 310 source : AC3 8) chain C residue 63 type sequence R description BINDING SITE FOR RESIDUE SO4 C 310 source : AC3 9) chain D residue 93 type sequence R description BINDING SITE FOR RESIDUE SO4 C 310 source : AC3 10) chain D residue 59 type sequence G description BINDING SITE FOR RESIDUE SO4 D 310 source : AC4 11) chain D residue 60 type sequence S description BINDING SITE FOR RESIDUE SO4 D 310 source : AC4 12) chain D residue 63 type sequence R description BINDING SITE FOR RESIDUE SO4 D 310 source : AC4 13) chain A residue 106-121 type prosite sequence SHGMGVPSIAIMLHEL description PNP_UDP_1 Purine and other phosphorylases family 1 signature. ShGMGvPSiAImlhEL source prosite : PS01232

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