eF-site ID 3ktm-G PDB Code 3ktm Chain G click to enlarge Title Structure of the Heparin-induced E1-Dimer of the Amyloid Precursor Protein (APP) Classification CELL ADHESION, SIGNALING PROTEIN Compound Amyloid beta A4 protein Source Homo sapiens (Human) (A4_HUMAN) Sequence G:  LLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKE GILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKT HPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETH LHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCC PLAIEGRKLAAALE Description Functional site 1) chain G residue 194 type sequence R description BINDING SITE FOR RESIDUE BU4 B 7 source : AC2 2) chain G residue 173 type sequence P description BINDING SITE FOR RESIDUE BU4 G 3 source : BC5 3) chain G residue 174 type sequence C description BINDING SITE FOR RESIDUE BU4 G 3 source : BC5 4) chain G residue 175 type sequence G description BINDING SITE FOR RESIDUE BU4 G 3 source : BC5 5) chain G residue 176 type sequence I description BINDING SITE FOR RESIDUE BU4 G 3 source : BC5 6) chain G residue 96 type BINDING sequence N description BINDING => ECO:0000269|PubMed:8158260 source Swiss-Prot : SWS_FT_FI1 7) chain G residue 168 type BINDING sequence Y description BINDING => ECO:0000255|PROSITE-ProRule:PRU01217, ECO:0000269|PubMed:17239395, ECO:0007744|PDB:2FK1 source Swiss-Prot : SWS_FT_FI3 8) chain G residue 147 type BINDING sequence H description BINDING => ECO:0000255|PROSITE-ProRule:PRU01217, ECO:0000269|PubMed:17239395, ECO:0000269|PubMed:25122912, ECO:0007744|PDB:2FK1 source Swiss-Prot : SWS_FT_FI2 9) chain G residue 151 type BINDING sequence H description BINDING => ECO:0000255|PROSITE-ProRule:PRU01217, ECO:0000269|PubMed:17239395, ECO:0000269|PubMed:25122912, ECO:0007744|PDB:2FK1 source Swiss-Prot : SWS_FT_FI2 10) chain G residue 183 type BINDING sequence E description BINDING => ECO:0000305|PubMed:8344894 source Swiss-Prot : SWS_FT_FI4 11) chain G residue 186 type BINDING sequence C description BINDING => ECO:0000305|PubMed:8344894 source Swiss-Prot : SWS_FT_FI4 12) chain G residue 187 type BINDING sequence C description BINDING => ECO:0000305|PubMed:8344894 source Swiss-Prot : SWS_FT_FI4 13) chain G residue 170 type SITE sequence M description Required for Cu(2+) reduction => ECO:0000255|PROSITE-ProRule:PRU01217 source Swiss-Prot : SWS_FT_FI5

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