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eF-site ID
|
3krx-B |
|
PDB Code
|
3krx |
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Chain
|
B |
|
click to enlarge
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Title
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Human GRK2 in complex with Gbetgamma subunits and balanol (co-crystal) |
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Classification
|
PROTEIN BINDING |
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Compound
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Beta-adrenergic receptor kinase 1 |
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Source
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null (GBG2_BOVIN) |
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Sequence
|
B: |
ELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGR
IQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIW
DSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICS
IYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSG
DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSG
ACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFA
TGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSG
RLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTD
DGMAVATGSWDSFLKIWN
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Description
|
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Functional site
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|
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1)
|
chain |
B |
| residue |
70-84 |
| type |
prosite |
| sequence |
LVSASQDGKLIIWDS
|
| description |
WD_REPEATS_1 Trp-Asp (WD) repeats signature. LVSAsqDgKLIIWDS
|
| source |
prosite : PS00678
|
|
|
2)
|
chain |
B |
| residue |
157-171 |
| type |
prosite |
| sequence |
IVTSSGDTTCALWDI
|
| description |
WD_REPEATS_1 Trp-Asp (WD) repeats signature. LVSAsqDgKLIIWDS
|
| source |
prosite : PS00678
|
|
|
3)
|
chain |
B |
| residue |
285-299 |
| type |
prosite |
| sequence |
LLAGYDDFNCNVWDA
|
| description |
WD_REPEATS_1 Trp-Asp (WD) repeats signature. LVSAsqDgKLIIWDS
|
| source |
prosite : PS00678
|
|
|
4)
|
chain |
B |
| residue |
266 |
| type |
MOD_RES |
| sequence |
H
|
| description |
Phosphohistidine => ECO:0000269|PubMed:12486123
|
| source |
Swiss-Prot : SWS_FT_FI2
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