eF-site ID 3kqi-A
PDB Code 3kqi
Chain A

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Title crystal structure of PHF2 PHD domain complexed with H3K4Me3 peptide
Classification NUCLEAR PROTEIN
Compound PHD finger protein 2
Source (H31_HUMAN)
Sequence A:  GSMATVPVYCVCRLPYDVTRFMIECDACKDWFHGSCVGVE
EEEAPDIDIYHCPNCEKTHGKSTLKKKRTWH
Description (1)  PHD finger protein 2


Functional site

1) chain A
residue 23
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 71
source : AC1

2) chain A
residue 26
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 71
source : AC1

3) chain A
residue 50
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 71
source : AC1

4) chain A
residue 53
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 71
source : AC1

5) chain A
residue 8
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 72
source : AC2

6) chain A
residue 10
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 72
source : AC2

7) chain A
residue 31
type
sequence H
description BINDING SITE FOR RESIDUE ZN A 72
source : AC2

8) chain A
residue 34
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 72
source : AC2

9) chain A
residue 53
type
sequence C
description BINDING SITE FOR RESIDUE GOL A 968
source : AC3

10) chain A
residue 56
type
sequence T
description BINDING SITE FOR RESIDUE GOL A 968
source : AC3

11) chain A
residue 57
type
sequence H
description BINDING SITE FOR RESIDUE GOL A 968
source : AC3

12) chain A
residue 57
type
sequence H
description BINDING SITE FOR RESIDUE GOL A 968
source : AC3

13) chain A
residue 64
type
sequence K
description BINDING SITE FOR RESIDUE CL A 73
source : AC4

14) chain A
residue 67
type
sequence T
description BINDING SITE FOR RESIDUE MG A 74
source : AC5

15) chain A
residue 33
type
sequence S
description BINDING SITE FOR RESIDUE MG A 75
source : AC6

16) chain A
residue 8-23
type prosite
sequence CVCRLPYDVTRFMIEC
description EGF_2 EGF-like domain signature 2. CvCrlPYdvtrfmieC
source prosite : PS01186

17) chain A
residue 8-53
type prosite
sequence CVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDI
YHCPNC
description ZF_PHD_1 Zinc finger PHD-type signature. Cv.Crlpydvtrfm...................................IeCda..Ckdw.FHgsCvgveeeeapdidi................................YhCpnC
source prosite : PS01359


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