|
|
eF-site ID
|
3kq6-C |
|
PDB Code
|
3kq6 |
|
Chain
|
C |
|
click to enlarge
|
|
|
Title
|
Enhancing the Therapeutic Properties of a Protein by a Designed Zinc-Binding Site, Structural principles of a novel long-acting insulin analog |
|
Classification
|
HORMONE |
|
Compound
|
Insulin A chain |
|
Source
|
null (INS_HUMAN) |
|
|
Sequence
|
C: |
GIVHQCCHSICSLYQLENYCN
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
C |
| residue |
4 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ZN A 301
|
| source |
: AC1
|
|
|
2)
|
chain |
C |
| residue |
3 |
| type |
|
| sequence |
V
|
| description |
BINDING SITE FOR RESIDUE CL A 302
|
| source |
: AC2
|
|
|
3)
|
chain |
C |
| residue |
6 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE IPH C 100
|
| source |
: AC4
|
|
|
4)
|
chain |
C |
| residue |
9 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE IPH C 100
|
| source |
: AC4
|
|
|
5)
|
chain |
C |
| residue |
10 |
| type |
|
| sequence |
I
|
| description |
BINDING SITE FOR RESIDUE IPH C 100
|
| source |
: AC4
|
|
|
6)
|
chain |
C |
| residue |
11 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE IPH C 100
|
| source |
: AC4
|
|
|
|