|
eF-site ID
|
3kq6-A |
PDB Code
|
3kq6 |
Chain
|
A |
|
click to enlarge
|
|
Title
|
Enhancing the Therapeutic Properties of a Protein by a Designed Zinc-Binding Site, Structural principles of a novel long-acting insulin analog |
Classification
|
HORMONE |
Compound
|
Insulin A chain |
Source
|
Homo sapiens (Human) (INS_HUMAN) |
|
Sequence
|
A: |
GIVHQCCHSICSLYQLENYCN
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
A |
residue |
4 |
type |
|
sequence |
H
|
description |
BINDING SITE FOR RESIDUE ZN A 301
|
source |
: AC1
|
|
2)
|
chain |
A |
residue |
8 |
type |
|
sequence |
H
|
description |
BINDING SITE FOR RESIDUE ZN A 301
|
source |
: AC1
|
|
3)
|
chain |
A |
residue |
4 |
type |
|
sequence |
H
|
description |
BINDING SITE FOR RESIDUE CL A 302
|
source |
: AC2
|
|
4)
|
chain |
A |
residue |
8 |
type |
|
sequence |
H
|
description |
BINDING SITE FOR RESIDUE CL A 302
|
source |
: AC2
|
|
5)
|
chain |
A |
residue |
6-20 |
type |
prosite |
sequence |
CCHSICSLYQLENYC
|
description |
INSULIN Insulin family signature. CCHSiCSlyqLenyC
|
source |
prosite : PS00262
|
|
|
|