|
|
eF-site ID
|
3kq6-A |
|
PDB Code
|
3kq6 |
|
Chain
|
A |
|
click to enlarge
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Title
|
Enhancing the Therapeutic Properties of a Protein by a Designed Zinc-Binding Site, Structural principles of a novel long-acting insulin analog |
|
Classification
|
HORMONE |
|
Compound
|
Insulin A chain |
|
Source
|
Homo sapiens (Human) (INS_HUMAN) |
|
|
Sequence
|
A: |
GIVHQCCHSICSLYQLENYCN
|
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
4 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ZN A 301
|
| source |
: AC1
|
|
|
2)
|
chain |
A |
| residue |
8 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ZN A 301
|
| source |
: AC1
|
|
|
3)
|
chain |
A |
| residue |
4 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE CL A 302
|
| source |
: AC2
|
|
|
4)
|
chain |
A |
| residue |
8 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE CL A 302
|
| source |
: AC2
|
|
|
5)
|
chain |
A |
| residue |
6-20 |
| type |
prosite |
| sequence |
CCHSICSLYQLENYC
|
| description |
INSULIN Insulin family signature. CCHSiCSlyqLenyC
|
| source |
prosite : PS00262
|
|
|
|