|
|
eF-site ID
|
3kq4-A |
|
PDB Code
|
3kq4 |
|
Chain
|
A |
|
click to enlarge
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Title
|
Structure of Intrinsic Factor-Cobalamin bound to its receptor Cubilin |
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Classification
|
TRANSPORT PROTEIN |
|
Compound
|
Gastric intrinsic factor |
|
Source
|
(CUBN_HUMAN) |
|
|
Sequence
|
A: |
SCSVPSAQEPLVNGIQVLMENSVTSSAYPNPSILIAMNLA
GAYNLKAQKLLTYQLMSSDNNDLTIGHLGLTIMALTSSCR
DPGDKVSILQRQMENWAPSSPNAEASAFYGPSLAILALCQ
KNSEATLPIAVRFAKTLLANSSPFNVDTGAMATLALTCMY
NKIPVGSEEGYRSLFGQVLKDIVEKISMKIKDNGIIGDIY
STGLAMQALSVTPEPSKKEWNCKKTTDMILNEIKQGKFHN
PMSIAQILPSLKGKTYLDVPQVTCSPDHEVQPTLPSASNI
TVIYTINNQLRGVELLFNETINVSVKSGSVLLVVLEEAQR
KNPMFKFETTMTSWGLVVSSINNIAENVNHKTYWQFLSGV
TPLNEGVADYIPFNHEHITANFTQY
|
|
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Description
|
(1) |
Gastric intrinsic factor, Cubilin
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
169-182 |
| type |
prosite |
| sequence |
NVDTGAMATLALTC
|
| description |
COBALAMIN_BINDING Eukaryotic cobalamin-binding proteins signature. NVDTGAMAtLALTC
|
| source |
prosite : PS00468
|
|
|
2)
|
chain |
A |
| residue |
311 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:20237569
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
3)
|
chain |
A |
| residue |
330 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
4)
|
chain |
A |
| residue |
334 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
5)
|
chain |
A |
| residue |
413 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17954916, ECO:0000269|PubMed:20237569
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
|
|