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|
eF-site ID
|
3kov-IJ |
|
PDB Code
|
3kov |
|
Chain
|
I, J |
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click to enlarge
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Title
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Structure of MEF2A bound to DNA reveals a completely folded MADS-box/MEF2 domain that recognizes DNA and recruits transcription co-factors |
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Classification
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TRANSCRIPTION/DNA |
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Compound
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Myocyte-specific enhancer factor 2A |
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Source
|
Homo sapiens (Human) (3KOV) |
|
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Sequence
|
I: |
GRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDC
EIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTN
SDIVEALNKK
|
| J: |
GRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDC
EIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTN
SDIVEALNKK
|
|
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Description
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Functional site
|
|
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1)
|
chain |
I |
| residue |
58-86 |
| type |
DNA_BIND |
| sequence |
ASTDMDKVLLKYTEYNEPHESRTNSDIVE
|
| description |
Mef2-type => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
J |
| residue |
58-86 |
| type |
DNA_BIND |
| sequence |
ASTDMDKVLLKYTEYNEPHESRTNSDIVE
|
| description |
Mef2-type => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
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chain |
I |
| residue |
59 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by CK2 => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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4)
|
chain |
J |
| residue |
59 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by CK2 => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|