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eF-site ID
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3kov-A |
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PDB Code
|
3kov |
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Chain
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A |
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click to enlarge
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Title
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Structure of MEF2A bound to DNA reveals a completely folded MADS-box/MEF2 domain that recognizes DNA and recruits transcription co-factors |
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Classification
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TRANSCRIPTION/DNA |
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Compound
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Myocyte-specific enhancer factor 2A |
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Source
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Homo sapiens (Human) (3KOV) |
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Sequence
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A: |
GRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDC
EIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTN
SDIVEALNKK
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Description
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Functional site
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1)
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chain |
A |
| residue |
3-57 |
| type |
prosite |
| sequence |
RKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCE
IALIIFNSSNKLFQY
|
| description |
MADS_BOX_1 MADS-box domain signature. RkKiqitrImDernRqvTFtKRKfgLmKKAyELSvLcdceIaLIIfnssnkLfqY
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| source |
prosite : PS00350
|
|
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2)
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chain |
A |
| residue |
58-86 |
| type |
DNA_BIND |
| sequence |
ASTDMDKVLLKYTEYNEPHESRTNSDIVE
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| description |
Mef2-type => ECO:0000255
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| source |
Swiss-Prot : SWS_FT_FI1
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3)
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chain |
A |
| residue |
59 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by CK2 => ECO:0000250
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| source |
Swiss-Prot : SWS_FT_FI2
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