eF-site/Summary 3kcv-I

eF-site ID	3kcv-I
PDB Code	3kcv
Chain	I

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Title	Structure of formate channel
Classification	TRANSPORT PROTEIN
Compound	Probable formate transporter 1
Source	null (FOCA_ECO57)

Sequence	I:	KHPLKTFYLAITAGVFISIAFVFYITATTGTGTMPFGMAK LVGGICFSLGLILCVVCGADLFTSTVLIVVAKASGRITWG QLAKNWLNVYFGNLVGALLFVLLMWLSGEYMTANGQWGLN VLQTADHKVHHTFIEAVCLGILANLMVCLAVWMSYSGRSL MDKAFIMVLPVAMFVASGFEHSIANMFMIPMGIVIRDFAS PEFWTAVGSAPENFSHLTVMNFITDNLIPVTIGNIIGGGL LVGLTYWVIYLR

Description

Functional site


1)	chain	I
	residue	91
	type	SITE
	sequence	T
	description	Important for formate translocation => ECO:0000250\|UniProtKB:P0AC23
	source	Swiss-Prot : SWS_FT_FI4

2)	chain	I
	residue	209
	type	SITE
	sequence	H
	description	Important for formate translocation => ECO:0000250\|UniProtKB:P0AC23
	source	Swiss-Prot : SWS_FT_FI4

3)	chain	I
	residue	86-112
	type	TOPO_DOM
	sequence	GADLFTSTVLIVVAKASGRITWGQLAK
	description	Cytoplasmic => ECO:0000269\|PubMed:19940917, ECO:0007744\|PDB:3KCU, ECO:0007744\|PDB:3KCV
	source	Swiss-Prot : SWS_FT_FI1

4)	chain	I
	residue	182-187
	type	TOPO_DOM
	sequence	SYSGRS
	description	Cytoplasmic => ECO:0000269\|PubMed:19940917, ECO:0007744\|PDB:3KCU, ECO:0007744\|PDB:3KCV
	source	Swiss-Prot : SWS_FT_FI1

5)	chain	I
	residue	31-56
	type	TRANSMEM
	sequence	PLKTFYLAITAGVFISIAFVFYITAT
	description	Helical => ECO:0000269\|PubMed:19940917, ECO:0007744\|PDB:3KCU, ECO:0007744\|PDB:3KCV
	source	Swiss-Prot : SWS_FT_FI2

6)	chain	I
	residue	65-85
	type	TRANSMEM
	sequence	GMAKLVGGICFSLGLILCVVC
	description	Helical => ECO:0000269\|PubMed:19940917, ECO:0007744\|PDB:3KCU, ECO:0007744\|PDB:3KCV
	source	Swiss-Prot : SWS_FT_FI2

7)	chain	I
	residue	113-135
	type	TRANSMEM
	sequence	NWLNVYFGNLVGALLFVLLMWLS
	description	Helical => ECO:0000269\|PubMed:19940917, ECO:0007744\|PDB:3KCU, ECO:0007744\|PDB:3KCV
	source	Swiss-Prot : SWS_FT_FI2

8)	chain	I
	residue	161-181
	type	TRANSMEM
	sequence	FIEAVCLGILANLMVCLAVWM
	description	Helical => ECO:0000269\|PubMed:19940917, ECO:0007744\|PDB:3KCU, ECO:0007744\|PDB:3KCV
	source	Swiss-Prot : SWS_FT_FI2

9)	chain	I
	residue	188-205
	type	TRANSMEM
	sequence	LMDKAFIMVLPVAMFVAS
	description	Helical => ECO:0000269\|PubMed:19940917, ECO:0007744\|PDB:3KCU, ECO:0007744\|PDB:3KCV
	source	Swiss-Prot : SWS_FT_FI2

10)	chain	I
	residue	250-276
	type	TRANSMEM
	sequence	FITDNLIPVTIGNIIGGGLLVGLTYWV
	description	Helical => ECO:0000269\|PubMed:19940917, ECO:0007744\|PDB:3KCU, ECO:0007744\|PDB:3KCV
	source	Swiss-Prot : SWS_FT_FI2

11)	chain	I
	residue	57-64
	type	TOPO_DOM
	sequence	TGTGTMPF
	description	Periplasmic => ECO:0000269\|PubMed:19940917, ECO:0007744\|PDB:3KCU, ECO:0007744\|PDB:3KCV
	source	Swiss-Prot : SWS_FT_FI3

12)	chain	I
	residue	136-160
	type	TOPO_DOM
	sequence	GEYMTANGQWGLNVLQTADHKVHHT
	description	Periplasmic => ECO:0000269\|PubMed:19940917, ECO:0007744\|PDB:3KCU, ECO:0007744\|PDB:3KCV
	source	Swiss-Prot : SWS_FT_FI3

13)	chain	I
	residue	206-249
	type	TOPO_DOM
	sequence	GFEHSIANMFMIPMGIVIRDFASPEFWTAVGSAPENFSHL TVMN
	description	Periplasmic => ECO:0000269\|PubMed:19940917, ECO:0007744\|PDB:3KCU, ECO:0007744\|PDB:3KCV
	source	Swiss-Prot : SWS_FT_FI3