eF-site ID 3k70-BCDEFG PDB Code 3k70 Chain B, C, D, E, F, G Title Crystal structure of the complete initiation complex of RecBCD Classification HYDROLASE/DNA Compound Exodeoxyribonuclease V beta chain Source Escherichia coli (strain K12) (3K70) Sequence B:  DVAETLDPLRLPLQGERLIEASAGTGKTFTIAALYLRLLL GLGGSAAFPRPLTVEELLVVTFTEAATAELRGRIRSNIHE LRIACLRETTDNPLYERLLEEIDDKAQAAQWLLLAERQMD EAAVFTIHGFCQRMLNLNAFESGMLFEQQLIEDESLLRYQ ACADFWRRHCYPLPREIAQVVFETWKGPQALLRDINRYLQ GEAPVIKAPPPDDETLASRHAQIVARIDTVKQQWRDAVGE LDALESSGIDRRKFNRSNQAKWIDKISAWAEEETNSYQLP ESLEKPRHPLFEAIDQLLAEPLSIRDLVITRALAEIRETV AREKRRRGELGFDDMLSRLDSALRSESGEVLAAAIRTRFP VAMIDEFQDTDPQQYRIFRRIWHHQPETALLLIGDPKQAI YAFRGADIFTYMKARSEVHAHYTLDTNWRSAPGMVNSVNK LFSQTDDAFMFREIPFIPVKSAGKNQALRFVFKGETQPAM KMWLMEGESCGVGDYQSTMAQVCAAQIRDWLQAGQRGEAL LMNGDDARPVRASDISVLVRSRQEAAQVRDALTLLEIPSV YLSNRDSVFETLEAQEMLWLLQAVMTPERENTLRSALATS MMGLNALDIETLNNDEHAWDVVVEEFDGYRQIWRKRGVMP MLRALMSARNIAENLLATAGGERRLTDILHISELLQEAGT QLESEHALVRWLSQHILEPDSNASSQQMRLESDKHLVQIV TIHKSKGLEYPLVWLPFITNFRVQEQAFYHDRHSFEAVLD LNAAPESVDLAEAERLAEDLRLLYVALTRSVWHCSLGVAP LVRRRGDKKGDTDVHQSALGRLLQKGEPQDAAGLRTCIEA LCDDDIAWQTAQTGDNQPWQVNDVSTAELNAKTLQRLPGD NWRVTSYSGLQQRGHGIAQDLMPRLDVDAAGVASVVEEPT LTPHQFPRGASPGTFLHSLFEDLDFTQPVDPNWVREKLEL GGFESQWEPVLTEWITAVLQAPLNETGVSLSQLSARNKQV EMEFYLPISEPLIASQLDTLIRQFDPLSAGCPPLEFMQVR GMLKGFIDLVFRHEGRYYLLDYKSNWLGEDSSAYTQQAMA AAMQAHRYDLQYQLYTLALHRYLRHRIADYDYEHHFGGVI YLFLRGVDKEHPQQGIYTTRPNAGLIALMDEMFAG C:  MLRVYHSNRLDVLEALMEFIVERERLDDPFEPEMILVQST GMAQWLQMTLSQKFGIAANIDFPLPASFIWDMFVRVLPEI PKESAFNKQSMSWKLMTLLPQLLEREDFTLLRHYLTDDSD KRKLFQLSSKAADLFDQYLVYRPDWLAQWETGHLVEGLGE AQAWQAPLWKALVEYTHQLGQPRWHRANLYQRFIETLESA TTCPPGLPSRVFICGISALPPVYLQALQALGKHIEIHLLF TNPCRYYWGDIKDPAYLAKLLTRQRRHSFEDRELPLFRDS ENAGQLFNSDGEQDVGNPLLASWGKLGRDYIYLLSDLESS QELDAFVDVTPDNLLHNIQSDILELENRAVAGVNIEEFSR SDNKRPLDPLDSSITFHVCHSPQREVEVLHDRLLAMLEED PTLTPRDIIVMVADIDSYSPFIQAVFGSAPADRYLPYAIS DRRARQSHPVLEAFISLLSLPDSRFVSEDVLALLDVPVLA ARFDITEEGLRYLRQWVNESGIRWGIDDDNVRELELPATG QHTWRFGLTRMLLGYAMESAQGEWQSVLPYDESSGLIAEL VGHLASLLMQLNIWRRGLAQERPLEEWLPVCRDMLNAFFL PDAETEAAMTLIEQQWQAIIAEGLGAQYGDAVPLSLLRDE LAQRLDQERISQRFLAGPVNICTLMPMRSIPFKVVCLLGM NDGVYPRQLAPLGFDLMSQKPKRGDRSRRDDDRYLFLEAL ISAQQKLYISYIGRSIQDNSERFPSVLVQELIDYIGQSHY LPGDEALNCDESEARVKAHLTCLHTRMPFDPQNYQPGERQ SYAREWLPAASQAGKAHSEFVQPLPFTLPETVPLETLQRF WAHPVRAFFQMRLQVNFRTEDSEIPDTEPFILEGLSRYQI NQQLLNALVEQDDAERLFRRFRAAGDLPYGAFGEIFWETQ CQEMQQLADRVIACRQPGQSMEIDLACNGVQITGWLPQVQ PDGLLRWRPSLLSVAQGMQLWLEHLVYCASGGNGESRLFL RKDGEWRFPPLAAEQALHYLSQLIEGYREGMSAPLLVLPE SGGAWLKTCYDAQNDAMLDDDSTLQKARTKFLQAYEGNMM VRGEGDDIWYQRLWRQLTPETMEAIVEQSQRFLLPLFRFN Q D:  MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAA LLSHDAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQN WEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVA RFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAV ALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIR LAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTL HRLLGAQPQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRL IDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFT AERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYRFG SDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGE DYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLC ALREGPFGVAGLNERIEQFMQQKRPSRLPEHETTWAMTVH KSQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSL YADERILSAAIATRTERRSGLAALFSS E:  DVAETLDPLRLPLQGERLIEASAGTGKTFTIAALYLRLLL GLGGSAAFPRPLTVEELLVVTFTEAATAELRGRIRSNIHE LRIACLRETTDNPLYERLLEEIDDKAQAAQWLLLAERQMD EAAVFTIHGFCQRMLNLNAFESGMLFEQQLIEDESLLRYQ ACADFWRRHCYPLPREIAQVVFETWKGPQALLRDINRYLQ GEAPVIKAPPPDDETLASRHAQIVARIDTVKQQWRDAVGE LDALESSGIDRRKFNRSNQAKWIDKISAWAEEETNSYQLP ESLEKPRHPLFEAIDQLLAEPLSIRDLVITRALAEIRETV AREKRRRGELGFDDMLSRLDSALRSESGEVLAAAIRTRFP VAMIDEFQDTDPQQYRIFRRIWHHQPETALLLIGDPKQAI YAFRGADIFTYMKARSEVHAHYTLDTNWRSAPGMVNSVNK LFSQTDDAFMFREIPFIPVKSAGKNQALRFVFKGETQPAM KMWLMEGESCGVGDYQSTMAQVCAAQIRDWLQAGQRGEAL LMNGDDARPVRASDISVLVRSRQEAAQVRDALTLLEIPSV YLSNRDSVFETLEAQEMLWLLQAVMTPERENTLRSALATS MMGLNALDIETLNNDEHAWDVVVEEFDGYRQIWRKRGVMP MLRALMSARNIAENLLATAGGERRLTDILHISELLQEAGT QLESEHALVRWLSQHILEPDSNASSQQMRLESDKHLVQIV TIHKSKGLEYPLVWLPFITNFRVQEQAFYHDRHSFEAVLD LNAAPESVDLAEAERLAEDLRLLYVALTRSVWHCSLGVAP LVRRRGDKKGDTDVHQSALGRLLQKGEPQDAAGLRTCIEA LCDDDIAWQTAQTGDNQPWQVNDVSTAELNAKTLQRLPGD NWRVTSYSGLQQRGHGIAQDLMPRLDVDAAGVASVVEEPT LTPHQFPRGASPGTFLHSLFEDLDFTQPVDPNWVREKLEL GGFESQWEPVLTEWITAVLQAPLNETGVSLSQLSARNKQV EMEFYLPISEPLIASQLDTLIRQFDPLSAGCPPLEFMQVR GMLKGFIDLVFRHEGRYYLLDYKSNWLGEDSSAYTQQAMA AAMQAHRYDLQYQLYTLALHRYLRHRIADYDYEHHFGGVI YLFLRGVDKEHPQQGIYTTRPNAGLIALMDEMFAG F:  MLRVYHSNRLDVLEALMEFIVERERLDDPFEPEMILVQST GMAQWLQMTLSQKFGIAANIDFPLPASFIWDMFVRVLPEI PKESAFNKQSMSWKLMTLLPQLLEREDFTLLRHYLTDDSD KRKLFQLSSKAADLFDQYLVYRPDWLAQWETGHLVEGLGE AQAWQAPLWKALVEYTHQLGQPRWHRANLYQRFIETLESA TTCPPGLPSRVFICGISALPPVYLQALQALGKHIEIHLLF TNPCRYYWGDIKDPAYLAKLLTRQRRHSFEDRELPLFRDS ENAGQLFNSDGEQDVGNPLLASWGKLGRDYIYLLSDLESS QELDAFVDVTPDNLLHNIQSDILELENRAVAGVNIEEFSR SDNKRPLDPLDSSITFHVCHSPQREVEVLHDRLLAMLEED PTLTPRDIIVMVADIDSYSPFIQAVFGSAPADRYLPYAIS DRRARQSHPVLEAFISLLSLPDSRFVSEDVLALLDVPVLA ARFDITEEGLRYLRQWVNESGIRWGIDDDNVRELELPATG QHTWRFGLTRMLLGYAMESAQGEWQSVLPYDESSGLIAEL VGHLASLLMQLNIWRRGLAQERPLEEWLPVCRDMLNAFFL PDAETEAAMTLIEQQWQAIIAEGLGAQYGDAVPLSLLRDE LAQRLDQERISQRFLAGPVNICTLMPMRSIPFKVVCLLGM NDGVYPRQLAPLGFDLMSQKPKRGDRSRRDDDRYLFLEAL ISAQQKLYISYIGRSIQDNSERFPSVLVQELIDYIGQSHY LPGDEALNCDESEARVKAHLTCLHTRMPFDPQNYQPGERQ SYAREWLPAASQAGKAHSEFVQPLPFTLPETVPLETLQRF WAHPVRAFFQMRLQVNFRTEDSEIPDTEPFILEGLSRYQI NQQLLNALVEQDDAERLFRRFRAAGDLPYGAFGEIFWETQ CQEMQQLADRVIACRQPGQSMEIDLACNGVQITGWLPQVQ PDGLLRWRPSLLSVAQGMQLWLEHLVYCASGGNGESRLFL RKDGEWRFPPLAAEQALHYLSQLIEGYREGMSAPLLVLPE SGGAWLKTCYDAQNDAMLDDDSTLQKARTKFLQAYEGNMM VRGEGDDIWYQRLWRQLTPETMEAIVEQSQRFLLPLFRFN Q G:  MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAA LLSHDAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQN WEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVA RFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAV ALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIR LAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTL HRLLGAQPQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRL IDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFT AERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYRFG SDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGE DYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLC ALREGPFGVAGLNERIEQFMQQKRPSRLPEHETTWAMTVH KSQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSL YADERILSAAIATRTERRSGLAALFSS Description Functional site 1) chain B residue 956 type sequence H description BINDING SITE FOR RESIDUE CA B 4000 source : AC1 2) chain B residue 1067 type sequence D description BINDING SITE FOR RESIDUE CA B 4000 source : AC1 3) chain B residue 1080 type sequence D description BINDING SITE FOR RESIDUE CA B 4000 source : AC1 4) chain B residue 1081 type sequence Y description BINDING SITE FOR RESIDUE CA B 4000 source : AC1 5) chain B residue 1082 type sequence K description BINDING SITE FOR RESIDUE CA B 4000 source : AC1 6) chain E residue 956 type sequence H description BINDING SITE FOR RESIDUE CA E 4000 source : AC2 7) chain E residue 1067 type sequence D description BINDING SITE FOR RESIDUE CA E 4000 source : AC2 8) chain E residue 1080 type sequence D description BINDING SITE FOR RESIDUE CA E 4000 source : AC2 9) chain E residue 1081 type sequence Y description BINDING SITE FOR RESIDUE CA E 4000 source : AC2 10) chain D residue 247 type DNA_BIND sequence Q description DNA_BIND => ECO:0000305 source Swiss-Prot : SWS_FT_FI1 11) chain G residue 247 type DNA_BIND sequence Q description DNA_BIND => ECO:0000305 source Swiss-Prot : SWS_FT_FI1 12) chain B residue 560-561 type DNA_BIND sequence SR description DNA_BIND => ECO:0000305 source Swiss-Prot : SWS_FT_FI1 13) chain B residue 761 type DNA_BIND sequence R description DNA_BIND => ECO:0000305 source Swiss-Prot : SWS_FT_FI1 14) chain E residue 252-254 type DNA_BIND sequence IDR description DNA_BIND => ECO:0000305 source Swiss-Prot : SWS_FT_FI1 15) chain E residue 511-512 type DNA_BIND sequence VG description DNA_BIND => ECO:0000305 source Swiss-Prot : SWS_FT_FI1 16) chain E residue 560-561 type DNA_BIND sequence SR description DNA_BIND => ECO:0000305 source Swiss-Prot : SWS_FT_FI1 17) chain E residue 761 type DNA_BIND sequence R description DNA_BIND => ECO:0000305 source Swiss-Prot : SWS_FT_FI1 18) chain B residue 956 type BINDING sequence H description BINDING => ECO:0000255|HAMAP-Rule:MF_01485, ECO:0000305|PubMed:15538360, ECO:0000305|PubMed:18668125 source Swiss-Prot : SWS_FT_FI5 19) chain B residue 1067 type BINDING sequence D description BINDING => ECO:0000255|HAMAP-Rule:MF_01485, ECO:0000305|PubMed:15538360, ECO:0000305|PubMed:18668125 source Swiss-Prot : SWS_FT_FI5 20) chain B residue 1080 type BINDING sequence D description BINDING => ECO:0000255|HAMAP-Rule:MF_01485, ECO:0000305|PubMed:15538360, ECO:0000305|PubMed:18668125 source Swiss-Prot : SWS_FT_FI5 21) chain E residue 956 type BINDING sequence H description BINDING => ECO:0000255|HAMAP-Rule:MF_01485, ECO:0000305|PubMed:15538360, ECO:0000305|PubMed:18668125 source Swiss-Prot : SWS_FT_FI5 22) chain E residue 1067 type BINDING sequence D description BINDING => ECO:0000255|HAMAP-Rule:MF_01485, ECO:0000305|PubMed:15538360, ECO:0000305|PubMed:18668125 source Swiss-Prot : SWS_FT_FI5 23) chain E residue 1080 type BINDING sequence D description BINDING => ECO:0000255|HAMAP-Rule:MF_01485, ECO:0000305|PubMed:15538360, ECO:0000305|PubMed:18668125 source Swiss-Prot : SWS_FT_FI5 24) chain B residue 1081 type BINDING sequence Y description BINDING => ECO:0000305|PubMed:15538360, ECO:0000305|PubMed:18668125 source Swiss-Prot : SWS_FT_FI6 25) chain E residue 1081 type BINDING sequence Y description BINDING => ECO:0000305|PubMed:15538360, ECO:0000305|PubMed:18668125 source Swiss-Prot : SWS_FT_FI6 26) chain D residue 171 type BINDING sequence G description BINDING => ECO:0000255|HAMAP-Rule:MF_01487 source Swiss-Prot : SWS_FT_FI2 27) chain G residue 171 type BINDING sequence G description BINDING => ECO:0000255|HAMAP-Rule:MF_01487 source Swiss-Prot : SWS_FT_FI2 28) chain B residue 23 type BINDING sequence A description BINDING => ECO:0000255|HAMAP-Rule:MF_01485, ECO:0000269|PubMed:15538360 source Swiss-Prot : SWS_FT_FI3 29) chain E residue 23 type BINDING sequence A description BINDING => ECO:0000255|HAMAP-Rule:MF_01485, ECO:0000269|PubMed:15538360 source Swiss-Prot : SWS_FT_FI3 30) chain B residue 447 type BINDING sequence W description BINDING => ECO:0000269|PubMed:15538360 source Swiss-Prot : SWS_FT_FI4 31) chain E residue 447 type BINDING sequence W description BINDING => ECO:0000269|PubMed:15538360 source Swiss-Prot : SWS_FT_FI4

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