|
|
eF-site ID
|
3jsv-D |
|
PDB Code
|
3jsv |
|
Chain
|
D |
|
click to enlarge
|
|
|
Title
|
Crystal structure of mouse NEMO CoZi in complex with Lys63-linked di-ubiquitin |
|
Classification
|
SIGNALING PROTEIN/TRANSCRIPTION |
|
Compound
|
Ubiquitin |
|
Source
|
null (NEMO_MOUSE) |
|
|
Sequence
|
D: |
LRQQLQQAEEALVAKQELIDKLKEEAEQHKIVMETVPVLK
AQADIYKADFQAERHAREKLVEKKEYLQEQLEQLQREFNK
LKVGCH
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
D |
| residue |
278 |
| type |
SITE |
| sequence |
K
|
| description |
Essential for function
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
2)
|
chain |
D |
| residue |
314 |
| type |
SITE |
| sequence |
K
|
| description |
Essential for function
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
D |
| residue |
318 |
| type |
SITE |
| sequence |
K
|
| description |
Essential for function
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
D |
| residue |
319 |
| type |
SITE |
| sequence |
K
|
| description |
Essential for function
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
D |
| residue |
270 |
| type |
SITE |
| sequence |
K
|
| description |
Interacts with activating enzyme
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
D |
| residue |
302 |
| type |
SITE |
| sequence |
K
|
| description |
Interacts with activating enzyme
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
7)
|
chain |
D |
| residue |
276 |
| type |
MOD_RES |
| sequence |
K
|
| description |
Phosphoserine; by PINK1 => ECO:0000269|PubMed:24660806, ECO:0000269|PubMed:24751536, ECO:0000269|PubMed:24784582, ECO:0000269|PubMed:25527291
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
8)
|
chain |
D |
| residue |
285 |
| type |
MOD_RES |
| sequence |
K
|
| description |
Phosphoserine; by PINK1 => ECO:0000269|PubMed:24660806, ECO:0000269|PubMed:24751536, ECO:0000269|PubMed:24784582, ECO:0000269|PubMed:25527291
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
9)
|
chain |
D |
| residue |
295 |
| type |
MOD_RES |
| sequence |
K
|
| description |
Phosphoserine; by PINK1 => ECO:0000269|PubMed:24660806, ECO:0000269|PubMed:24751536, ECO:0000269|PubMed:24784582, ECO:0000269|PubMed:25527291
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|