eF-site ID 3jbl-G PDB Code 3jbl Chain G click to enlarge Title Cryo-EM Structure of the Activated NAIP2/NLRC4 Inflammasome Reveals Nucleated Polymerization Classification IMMUNE SYSTEM Compound NLR family CARD domain-containing protein 4 Source (NLRC4_MOUSE) Sequence G:  VTEEDLNVLAQNLKDLYNSPAFLNFYPLGEDIDIIFNLEK TFTEPIMWKKDHRHHRVEQLTLGSLLEALKSPCLIEGESG KGKSTLLQRIAMLWASGGCRALKGFRLVFFIHLRSARGGL FETLYDQLLNIPDFISKPTFKALLLKLHKEVLFLLDGYNE FHPQNCPEIEALIKENHRFKNMVIVTTTTECLRHIRHVGA LTAEVGDMTEDSAKDLIEAVLVPDQVERLWAQIQESRCLR NLMKTPLFVVITCAIQMGRQEFQAHTQTMLFQTFYDLLIQ KNSHRYRGGASGDFARSLDYCGDLALEGVFAHKFDFEPEH GSSMNEDVLVTIGLLCKYTAQRLKPTYKFFHKSFQEYTAG RRLSSLLTSKEPEEVSKGNSYLNKMVSISDITSLYGNLLL YTCGSSTEATRAVMRHLAMVYQHGSLQGLSVTKRPLWRQE XIQSLRNTTEQDVLKAINVNSFVECGINLFSESMSKSDLS QEFEAFFQGKSLYINSENIPDYLFDFFEYLPNCASALDFV KLDFYERATPPRAVSLFFNWKQEFKTLEVTLRDINKLNKQ DIKYLGKIFSSATNLRLHIKRCAAMAGRLSSVLRTCKNMH TLMVEASPLTTDDEQYITSVTGLQNLSIHRLHTQQLPGGL IDSLGNLKNLERLILDDIRMNEEDAKNLAEGLRSLKKMRL LHLTHLSDIGEGMDYIVKSLSEESCDLQEMKLVACCLTAN SVKVLAQNLHNLIKLSILDISENYLEKDGNEALQELIGRL GVLGELTTLMLPWCWDVHTSLPKLLKQLEGTPGLAKLGLK NWRLRDEEIKSLGEFLEMNPLRDLQQLDLAGHCVSSDGWL YFMNVFENLKQLVFFDFSTEEFLPDAALVRKLSQVLSKLT LLQEVKLTGWEFDDYDISAIKGTFKLVTA Description (1)  NLR family CARD domain-containing protein 4 Functional site 1) chain G residue 135 type BINDING sequence T description BINDING => ECO:0000269|PubMed:23765277, ECO:0007744|PDB:4KXF source Swiss-Prot : SWS_FT_FI1 2) chain G residue 172 type BINDING sequence G description BINDING => ECO:0000269|PubMed:23765277, ECO:0007744|PDB:4KXF source Swiss-Prot : SWS_FT_FI1 3) chain G residue 443 type BINDING sequence H description BINDING => ECO:0000269|PubMed:23765277, ECO:0007744|PDB:4KXF source Swiss-Prot : SWS_FT_FI1 4) chain G residue 533 type MOD_RES sequence X description Phosphoserine => ECO:0000269|PubMed:22885697, ECO:0000269|PubMed:23765277 source Swiss-Prot : SWS_FT_FI2

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