eF-site ID 3jad-E PDB Code 3jad Chain E click to enlarge Title Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, strychnine-bound state Classification SIGNALING PROTEIN/ANTAGONIST Compound Glycine receptor subunit alphaZ1 Source (3JAD) Sequence E:  APSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSF GSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPS MLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLY SIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIF EWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFT CIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDA APARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMA VCLLFVFSALLEYAAVNFIARKLFISRAKRIDTVSRVAFP LVFLIFNIFYWITYKLV Description (1)  zebra fish alpha1 glycine receptor Functional site 1) chain E residue 239-260 type TRANSMEM sequence YLIQMYIPSLLIVILSWVSFWI description Helical; Name=1 => ECO:0000269|PubMed:26344198 source Swiss-Prot : SWS_FT_FI1 2) chain E residue 54 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255, ECO:0000269|PubMed:26344198 source Swiss-Prot : SWS_FT_FI10 3) chain E residue 261-265 type TOPO_DOM sequence NMDAA description Cytoplasmic => ECO:0000269|PubMed:26344198 source Swiss-Prot : SWS_FT_FI2 4) chain E residue 266-286 type TRANSMEM sequence PARVGLGITTVLTMTTQSSGS description Helical; Name=2 => ECO:0000269|PubMed:26344198 source Swiss-Prot : SWS_FT_FI3 5) chain E residue 287-297 type TOPO_DOM sequence RASLPKVSYVK description Extracellular => ECO:0000269|PubMed:26344198 source Swiss-Prot : SWS_FT_FI4 6) chain E residue 298-318 type TRANSMEM sequence AIDIWMAVCLLFVFSALLEYA description Helical; Name=3 => ECO:0000269|PubMed:26344198 source Swiss-Prot : SWS_FT_FI5 7) chain E residue 208 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:P23415 source Swiss-Prot : SWS_FT_FI7 8) chain E residue 210 type BINDING sequence D description BINDING => ECO:0000250|UniProtKB:P23415 source Swiss-Prot : SWS_FT_FI7 9) chain E residue 231 type BINDING sequence H description BINDING => ECO:0000250|UniProtKB:P23415 source Swiss-Prot : SWS_FT_FI7 10) chain E residue 218 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:26344198 source Swiss-Prot : SWS_FT_FI8 11) chain E residue 277 type SITE sequence L description Important for obstruction of the ion pore in the closed conformation => ECO:0000269|PubMed:26344198 source Swiss-Prot : SWS_FT_FI9

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