eF-site ID 3jac-C PDB Code 3jac Chain C click to enlarge Title Cryo-EM study of a channel Classification METAL TRANSPORT Compound Piezo-type mechanosensitive ion channel component 1 Source (3JAC) Sequence C:  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXXXXXFFHDILHTKYRAAT DVYALMFLADIVDIIIIIFGFWAFGKHSAATDIASSLSDD QVPQAFLFMLLVQFGTMVIDRALYLRKTVLGKLAFQVVLV VAIHIWMFFILPAVTERMFSQNAVAQLWYFVKCIYFALSA YQIRCGYPTRILGNFLTKKYNHLNLFLFQGFRLVPFLVEL RAVMDWVWTDTTLSLSNWMCVEDIYANIFIIKCSRETEKK YPQPKGQKKKKIVKYGMGGLIILFLIAIIWFPLLFMSLIR SVVGVVNQPIDVTVTLKLGGYEPLFTMSAQQPSIVPFTPQ AYEELSQQFDPYPLAMQFISQYSPEDIVTAQIEGSSGALW RISPPSRAQMKQELYNGTADITLRFTWNFQRDLAKGGTVE YTNEKHTLELAPNSTARRQLAQLLEGRPDQSVVIPHLFPK YIRAPNGPEANPVKQLQPDEEEDYLGVRIQLRREQVGSDF LEWWVIELQDCKADCNLLPMVIFSDKVSPPSLGFLAGYGI VGLYVSIVLVVGKFVRGFFSEISHSIMFEELPCVDRILKL CQDIFLVRETRELELEEELYAKLIFLYRSPETMIKWTR Description (1)  Piezo-type mechanosensitive ion channel component 1 Functional site 1) chain C residue 1978-1998 type TRANSMEM sequence ALMFLADIVDIIIIIFGFWAF description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 2) chain C residue 2019-2039 type TRANSMEM sequence AFLFMLLVQFGTMVIDRALYL description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 3) chain C residue 2048-2068 type TRANSMEM sequence AFQVVLVVAIHIWMFFILPAV description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 4) chain C residue 2077-2097 type TRANSMEM sequence AVAQLWYFVKCIYFALSAYQI description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 5) chain C residue 2145-2165 type TRANSMEM sequence TTLSLSNWMCVEDIYANIFII description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 6) chain C residue 2193-2213 type TRANSMEM sequence GLIILFLIAIIWFPLLFMSLI description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 7) chain C residue 2458-2478 type TRANSMEM sequence LGFLAGYGIVGLYVSIVLVVG description Helical => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 8) chain C residue 2214-2457 type TOPO_DOM sequence RSVVGVVNQPIDVTVTLKLGGYEPLFTMSAQQPSIVPFTP QAYEELSQQFDPYPLAMQFISQYSPEDIVTAQIEGSSGAL WRISPPSRAQMKQELYNGTADITLRFTWNFQRDLAKGGTV EYTNEKHTLELAPNSTARRQLAQLLEGRPDQSVVIPHLFP KYIRAPNGPEANPVKQLQPDEEEDYLGVRIQLRREQVGSD FLEWWVIELQDCKADCNLLPMVIFSDKVSPPS description Extracellular => ECO:0000269|PubMed:26390154 source Swiss-Prot : SWS_FT_FI2

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