|
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eF-site ID
|
3j96-E |
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PDB Code
|
3j96 |
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Chain
|
E |
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click to enlarge
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Title
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Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State I) |
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Classification
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HYDROLASE |
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Compound
|
Vesicle-fusing ATPase |
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Source
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(3J96) |
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Sequence
|
E: |
MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTS
PNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEV
ALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAE
FIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMRQKIE
VGLVVGNSQVAFEKAENSSLNLIGKAKTKMGIGGLDKEFS
DIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTL
LARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFAD
AEEEQRRLGANSGLHIIIFDEIHDTVVNQLLSKIDGVEQL
NNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRL
QILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGL
VRAAQSTAMNRHIDFLASLENDIKPAFGTEDYASYIMNGI
IKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHS
GKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKK
IFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALL
VLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHV
PNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGI
KKLLMLIEMSLQMDPEYRVRKFLALLREEG
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Description
|
|
Functional site
|
|
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1)
|
chain |
E |
| residue |
549 |
| type |
catalytic |
| sequence |
K
|
| description |
642
|
| source |
MCSA : MCSA5
|
|
|
2)
|
chain |
E |
| residue |
550 |
| type |
catalytic |
| sequence |
T
|
| description |
642
|
| source |
MCSA : MCSA5
|
|
|
3)
|
chain |
E |
| residue |
603 |
| type |
catalytic |
| sequence |
D
|
| description |
642
|
| source |
MCSA : MCSA5
|
|
|
4)
|
chain |
E |
| residue |
604 |
| type |
catalytic |
| sequence |
D
|
| description |
642
|
| source |
MCSA : MCSA5
|
|
|
5)
|
chain |
E |
| residue |
631 |
| type |
catalytic |
| sequence |
K
|
| description |
642
|
| source |
MCSA : MCSA5
|
|
|
6)
|
chain |
E |
| residue |
708 |
| type |
catalytic |
| sequence |
K
|
| description |
642
|
| source |
MCSA : MCSA5
|
|
|
7)
|
chain |
E |
| residue |
545 |
| type |
SITE |
| sequence |
P
|
| description |
(Microbial infection) Cleavage; by C.botulinum neurotoxin type E (BoNT/E) => ECO:0000269|PubMed:8243676, ECO:0000269|PubMed:8294407, ECO:0000305|PubMed:8103915
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
8)
|
chain |
E |
| residue |
505 |
| type |
SITE |
| sequence |
N
|
| description |
(Microbial infection) Cleavage; by C.botulinum neurotoxin type E (BoNT/E) => ECO:0000269|PubMed:8243676, ECO:0000269|PubMed:8294407, ECO:0000305|PubMed:8103915
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
9)
|
chain |
E |
| residue |
550 |
| type |
SITE |
| sequence |
T
|
| description |
(Microbial infection) Cleavage; by C.botulinum neurotoxin type A (BoNT/A, botA) => ECO:0000269|PubMed:8243676, ECO:0000269|PubMed:8294407, ECO:0000305|PubMed:8103915
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
10)
|
chain |
E |
| residue |
259 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Phosphoserine; by PKC => ECO:0000269|PubMed:12459461
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
11)
|
chain |
E |
| residue |
569 |
| type |
LIPID |
| sequence |
S
|
| description |
S-palmitoyl cysteine => ECO:0000250|UniProtKB:P60879
|
| source |
Swiss-Prot : SWS_FT_FI6
|
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|
|