|
|
eF-site ID
|
3j95-A |
|
PDB Code
|
3j95 |
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Chain
|
A |
|
click to enlarge
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Title
|
Structure of ADP-bound N-ethylmaleimide sensitive factor determined by single particle cryoelectron microscopy |
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Classification
|
HYDROLASE |
|
Compound
|
Vesicle-fusing ATPase |
|
Source
|
(NSF_CRIGR) |
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Sequence
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A: |
FEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVK
GILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKY
VGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAIC
HDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRP
GRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDI
KELAVETKNFSGAELEGLVRAAQSTAMNRHIDFLASLEND
IKEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRT
PLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMI
GFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPI
GPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQE
MEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTI
AQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLR
EEG
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|
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Description
|
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Functional site
|
|
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1)
|
chain |
A |
| residue |
549 |
| type |
catalytic |
| sequence |
K
|
| description |
642
|
| source |
MCSA : MCSA1
|
|
|
2)
|
chain |
A |
| residue |
550 |
| type |
catalytic |
| sequence |
T
|
| description |
642
|
| source |
MCSA : MCSA1
|
|
|
3)
|
chain |
A |
| residue |
603 |
| type |
catalytic |
| sequence |
D
|
| description |
642
|
| source |
MCSA : MCSA1
|
|
|
4)
|
chain |
A |
| residue |
604 |
| type |
catalytic |
| sequence |
D
|
| description |
642
|
| source |
MCSA : MCSA1
|
|
|
5)
|
chain |
A |
| residue |
631 |
| type |
catalytic |
| sequence |
K
|
| description |
642
|
| source |
MCSA : MCSA1
|
|
|
6)
|
chain |
A |
| residue |
708 |
| type |
catalytic |
| sequence |
K
|
| description |
642
|
| source |
MCSA : MCSA1
|
|
|
7)
|
chain |
A |
| residue |
367-385 |
| type |
prosite |
| sequence |
ILVIGMTNRPDLIDEALLR
|
| description |
AAA AAA-protein family signature. IlVIgMTNrpdlIDeALl.R
|
| source |
prosite : PS00674
|
|
|
8)
|
chain |
A |
| residue |
505 |
| type |
BINDING |
| sequence |
N
|
| description |
BINDING => ECO:0000269|PubMed:9731775, ECO:0000305|PubMed:9727495
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
9)
|
chain |
A |
| residue |
545 |
| type |
BINDING |
| sequence |
P
|
| description |
BINDING => ECO:0000269|PubMed:9731775, ECO:0000305|PubMed:9727495
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
10)
|
chain |
A |
| residue |
550 |
| type |
BINDING |
| sequence |
T
|
| description |
BINDING => ECO:0000269|PubMed:9731775
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
11)
|
chain |
A |
| residue |
259 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Phosphotyrosine => ECO:0000250|UniProtKB:P46460
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
12)
|
chain |
A |
| residue |
569 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by CDK16 => ECO:0000250|UniProtKB:P46460
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
|
|