eF-site ID 3j94-D PDB Code 3j94 Chain D click to enlarge Title Structure of ATP-bound N-ethylmaleimide sensitive factor determined by single particle cryoelectron microscopy Classification HYDROLASE Compound Vesicle-fusing ATPase Source (NSF_CRIGR) Sequence D:  KMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGI LLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVG ESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAIDTV VNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLE VKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELA VETKNFSGAELEGLVRAAQSTAMNRHIFLASLENDIKPAF GTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSD RTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDK MIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYV PIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVL QEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERT TIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLAL LREEG Description Functional site 1) chain D residue 502 type sequence Y description BINDING SITE FOR RESIDUE ATP D 801 source : AC7 2) chain D residue 503 type sequence I description BINDING SITE FOR RESIDUE ATP D 801 source : AC7 3) chain D residue 504 type sequence M description BINDING SITE FOR RESIDUE ATP D 801 source : AC7 4) chain D residue 505 type sequence N description BINDING SITE FOR RESIDUE ATP D 801 source : AC7 5) chain D residue 506 type sequence G description BINDING SITE FOR RESIDUE ATP D 801 source : AC7 6) chain D residue 507 type sequence I description BINDING SITE FOR RESIDUE ATP D 801 source : AC7 7) chain D residue 508 type sequence I description BINDING SITE FOR RESIDUE ATP D 801 source : AC7 8) chain D residue 544 type sequence P description BINDING SITE FOR RESIDUE ATP D 801 source : AC7 9) chain D residue 545 type sequence P description BINDING SITE FOR RESIDUE ATP D 801 source : AC7 10) chain D residue 546 type sequence H description BINDING SITE FOR RESIDUE ATP D 801 source : AC7 11) chain D residue 547 type sequence S description BINDING SITE FOR RESIDUE ATP D 801 source : AC7 12) chain D residue 548 type sequence G description BINDING SITE FOR RESIDUE ATP D 801 source : AC7 13) chain D residue 549 type sequence K description BINDING SITE FOR RESIDUE ATP D 801 source : AC7 14) chain D residue 550 type sequence T description BINDING SITE FOR RESIDUE ATP D 801 source : AC7 15) chain D residue 551 type sequence A description BINDING SITE FOR RESIDUE ATP D 801 source : AC7 16) chain D residue 707 type sequence I description BINDING SITE FOR RESIDUE ATP D 801 source : AC7 17) chain D residue 708 type sequence K description BINDING SITE FOR RESIDUE ATP D 801 source : AC7 18) chain D residue 221 type sequence G description BINDING SITE FOR RESIDUE ATP D 802 source : AC8 19) chain D residue 222 type sequence G description BINDING SITE FOR RESIDUE ATP D 802 source : AC8 20) chain D residue 263 type sequence G description BINDING SITE FOR RESIDUE ATP D 802 source : AC8 21) chain D residue 264 type sequence C description BINDING SITE FOR RESIDUE ATP D 802 source : AC8 22) chain D residue 265 type sequence G description BINDING SITE FOR RESIDUE ATP D 802 source : AC8 23) chain D residue 266 type sequence K description BINDING SITE FOR RESIDUE ATP D 802 source : AC8 24) chain D residue 267 type sequence T description BINDING SITE FOR RESIDUE ATP D 802 source : AC8 25) chain D residue 268 type sequence L description BINDING SITE FOR RESIDUE ATP D 802 source : AC8 26) chain D residue 374 type sequence N description BINDING SITE FOR RESIDUE ATP D 802 source : AC8 27) chain D residue 406 type sequence I description BINDING SITE FOR RESIDUE ATP D 802 source : AC8 28) chain D residue 438 type sequence G description BINDING SITE FOR RESIDUE ATP D 802 source : AC8 29) chain D residue 439 type sequence A description BINDING SITE FOR RESIDUE ATP D 802 source : AC8 30) chain D residue 442 type sequence E description BINDING SITE FOR RESIDUE ATP D 802 source : AC8 31) chain D residue 631 type sequence K description BINDING SITE FOR RESIDUE ATP E 801 source : AC9 32) chain D residue 382 type sequence A description BINDING SITE FOR RESIDUE ATP E 802 source : BC1 33) chain D residue 388 type sequence R description BINDING SITE FOR RESIDUE ATP E 802 source : BC1 34) chain D residue 505 type BINDING sequence N description BINDING => ECO:0000269|PubMed:9731775, ECO:0000305|PubMed:9727495 source Swiss-Prot : SWS_FT_FI1 35) chain D residue 545 type BINDING sequence P description BINDING => ECO:0000269|PubMed:9731775, ECO:0000305|PubMed:9727495 source Swiss-Prot : SWS_FT_FI1 36) chain D residue 550 type BINDING sequence T description BINDING => ECO:0000269|PubMed:9731775 source Swiss-Prot : SWS_FT_FI2 37) chain D residue 259 type MOD_RES sequence Y description Phosphotyrosine => ECO:0000250|UniProtKB:P46460 source Swiss-Prot : SWS_FT_FI5 38) chain D residue 569 type MOD_RES sequence S description Phosphoserine; by CDK16 => ECO:0000250|UniProtKB:P46460 source Swiss-Prot : SWS_FT_FI6 39) chain D residue 631 type catalytic sequence K description 642 source MCSA : MCSA4 40) chain D residue 549 type catalytic sequence K description 642 source MCSA : MCSA4 41) chain D residue 550 type catalytic sequence T description 642 source MCSA : MCSA4 42) chain D residue 603 type catalytic sequence D description 642 source MCSA : MCSA4 43) chain D residue 604 type catalytic sequence D description 642 source MCSA : MCSA4 44) chain D residue 708 type catalytic sequence K description 642 source MCSA : MCSA4

Display surface Download Links