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eF-site ID
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3j79-D |
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PDB Code
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3j79 |
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Chain
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D |
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click to enlarge
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Title
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Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, large subunit |
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Classification
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RIBOSOME/INHIBITOR |
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Compound
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28S ribosomal RNA |
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Source
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ORGANISM_SCIENTIFIC: Plasmodium falciparum; |
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Sequence
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D: |
GRVIRGQRKGRGSIFKSHNHHRKGAAKLRHLDYCEKKGYI
KGLVKDIIHDPGRGAPLAKVIFKRTEKYGKKEELIIASEG
MFTGQYISCGTKAPLSVGNILPIGKMPEGTLICNLEHRTG
NRGTLVKASGCYATVVGQSEDGKKTKVRLPSGAKKTIDAK
ARAMVGVVGAGGRIDKPILKAGVAHHKYRVKRNCWPKVRG
VAMNPVEHPHGGGNHQHIGHPSTVSRSAPAGQKVGLIAAR
RTGLLRG
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Description
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Functional site
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1)
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chain |
D |
| residue |
206 |
| type |
|
| sequence |
P
|
| description |
BINDING SITE FOR RESIDUE MG A 3815
|
| source |
: BC6
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|
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2)
|
chain |
D |
| residue |
205 |
| type |
|
| sequence |
N
|
| description |
BINDING SITE FOR RESIDUE MG A 3817
|
| source |
: BC8
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|
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3)
|
chain |
D |
| residue |
198 |
| type |
|
| sequence |
K
|
| description |
BINDING SITE FOR RESIDUE MG A 3919
|
| source |
: MC7
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|
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4)
|
chain |
D |
| residue |
200 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE MG A 3919
|
| source |
: MC7
|
|
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5)
|
chain |
D |
| residue |
197-208 |
| type |
prosite |
| sequence |
PKVRGVAMNPVE
|
| description |
RIBOSOMAL_L2 Ribosomal protein L2 signature. PkvRGVAmNPvE
|
| source |
prosite : PS00467
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