|
|
eF-site ID
|
3j79-h |
|
PDB Code
|
3j79 |
|
Chain
|
h |
|
click to enlarge
|
|
|
Title
|
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, large subunit |
|
Classification
|
RIBOSOME/INHIBITOR |
|
Compound
|
28S ribosomal RNA |
|
Source
|
ORGANISM_SCIENTIFIC: Plasmodium falciparum; |
|
|
Sequence
|
h: |
SRRTKKVGLTGKYGTRYGSSLRKQIKKIELMQHAKYLCTF
CGKTATKRTCVGIWKCKKCKRKVCGGAWSLTTPAAVAAKS
TIIRL
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
h |
| residue |
39 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN h 100
|
| source |
: RC9
|
|
|
2)
|
chain |
h |
| residue |
42 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN h 100
|
| source |
: RC9
|
|
|
3)
|
chain |
h |
| residue |
57 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN h 100
|
| source |
: RC9
|
|
|
4)
|
chain |
h |
| residue |
60 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN h 100
|
| source |
: RC9
|
|
|
5)
|
chain |
h |
| residue |
39-60 |
| type |
ZN_FING |
| sequence |
CTFCGKTATKRTCVGIWKCKKC
|
| description |
C4-type
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|