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eF-site ID
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3j79-a |
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PDB Code
|
3j79 |
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Chain
|
a |
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click to enlarge
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Title
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Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, large subunit |
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Classification
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RIBOSOME/INHIBITOR |
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Compound
|
28S ribosomal RNA |
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Source
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ORGANISM_SCIENTIFIC: Plasmodium falciparum; |
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Sequence
|
a: |
AQRVHYRRHNHYNTKSNKVRPVRTPGGKLTIHVVKKKAGK
PKCADCKTAIQGVKALRPADNYRARRKNRTVARAYGGSIC
ARCIRERIMRAFLFEEQKCVRQVLKE
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Description
|
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Functional site
|
|
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1)
|
chain |
a |
| residue |
44 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN a 200
|
| source |
: RC6
|
|
|
2)
|
chain |
a |
| residue |
47 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN a 200
|
| source |
: RC6
|
|
|
3)
|
chain |
a |
| residue |
49 |
| type |
|
| sequence |
T
|
| description |
BINDING SITE FOR RESIDUE ZN a 200
|
| source |
: RC6
|
|
|
4)
|
chain |
a |
| residue |
81 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN a 200
|
| source |
: RC6
|
|
|
5)
|
chain |
a |
| residue |
84 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN a 200
|
| source |
: RC6
|
|
|
6)
|
chain |
a |
| residue |
15-28 |
| type |
prosite |
| sequence |
TKSNKVRPVRTPGG
|
| description |
RIBOSOMAL_L34E Ribosomal protein L34e signature. TkSnKvrpvRTPGG
|
| source |
prosite : PS01145
|
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