eF-site ID 3j5m-ABCDEFGHIJKL PDB Code 3j5m Chain A, B, C, D, E, F, G, H, I, J, K, L click to enlarge Title Cryo-EM structure of the BG505 SOSIP.664 HIV-1 Env trimer with 3 PGV04 Fabs Classification VIRAL PROTEIN/IMMUNE SYSTEM Compound BG505 SOSIP gp120 Source (3J5M) Sequence A:  VWKDAETTLFCASDAKAYETEKHNVWATHACVPTDPNPQE IHLENVTEEFNMWKNNMVEQMHTDIISLWDQSLKPCVKLT PLCVTLQCTNVTNNITDDMRGELKNCSFNMTTELRDKKQK VYSLFYRYRLINCNTSAITQACPKVSFEPIPIHYCAPAGF AILKCKDKKFNGTGPCPSVSTVQCTHGIKPVVSTQLLLNG SLAEEEVMIRSENITNNAKNILVQFNTPVQINCTRPNNNT RKSIRIGPGQAFYATGDIIGDIRQAHCNVSKATWNETLGK VVKQLRKHFGNNTIIRFANSSGGDLEVTTHSFNCGGEFFY CNTSGLFNSTWISNDSITLPCRIKQIINMWQRIGQAMYAP PIQGVIRCVSNITGLILTRDGGSTNSTTETFRPGGGDMRD NWRSELYKYKVVKIE B:  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX C:  EIVLTQSPGTLSLSPGETASLSCTAASYGHMTWYQKKPGQ PPKLLIFATSKRASGIPDRFSGSQFGKQYTLTITRMEPED FARYYCQQLEFFGQGTRLEIRRTVAAPSVFIFPPSDEQLK SGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQ DSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVT KSFNRGEC D:  QVQLVQSGSGVKKPGASVRVSCWTSEDIFERTELIHWVRQ APGQGLEWIGWVKTVTGAVNFGSPDFRQRVSLTRDRDLFT AHMDIRGLTQGDTATYFCARQKFYTGGQGWYFDLWGRGTL IVVSSASTKGPSVFPLAPSSKSGGTAALGCLVKDYFPEPV TVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLG TQTYICNVNHKPSNTKVDKKVEPKS E:  VWKDAETTLFCASDAKAYETEKHNVWATHACVPTDPNPQE IHLENVTEEFNMWKNNMVEQMHTDIISLWDQSLKPCVKLT PLCVTLQCTNVTNNITDDMRGELKNCSFNMTTELRDKKQK VYSLFYRYRLINCNTSAITQACPKVSFEPIPIHYCAPAGF AILKCKDKKFNGTGPCPSVSTVQCTHGIKPVVSTQLLLNG SLAEEEVMIRSENITNNAKNILVQFNTPVQINCTRPNNNT RKSIRIGPGQAFYATGDIIGDIRQAHCNVSKATWNETLGK VVKQLRKHFGNNTIIRFANSSGGDLEVTTHSFNCGGEFFY CNTSGLFNSTWISNDSITLPCRIKQIINMWQRIGQAMYAP PIQGVIRCVSNITGLILTRDGGSTNSTTETFRPGGGDMRD NWRSELYKYKVVKIE F:  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX G:  EIVLTQSPGTLSLSPGETASLSCTAASYGHMTWYQKKPGQ PPKLLIFATSKRASGIPDRFSGSQFGKQYTLTITRMEPED FARYYCQQLEFFGQGTRLEIRRTVAAPSVFIFPPSDEQLK SGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQ DSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVT KSFNRGEC H:  QVQLVQSGSGVKKPGASVRVSCWTSEDIFERTELIHWVRQ APGQGLEWIGWVKTVTGAVNFGSPDFRQRVSLTRDRDLFT AHMDIRGLTQGDTATYFCARQKFYTGGQGWYFDLWGRGTL IVVSSASTKGPSVFPLAPSSKSGGTAALGCLVKDYFPEPV TVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLG TQTYICNVNHKPSNTKVDKKVEPKS I:  VWKDAETTLFCASDAKAYETEKHNVWATHACVPTDPNPQE IHLENVTEEFNMWKNNMVEQMHTDIISLWDQSLKPCVKLT PLCVTLQCTNVTNNITDDMRGELKNCSFNMTTELRDKKQK VYSLFYRYRLINCNTSAITQACPKVSFEPIPIHYCAPAGF AILKCKDKKFNGTGPCPSVSTVQCTHGIKPVVSTQLLLNG SLAEEEVMIRSENITNNAKNILVQFNTPVQINCTRPNNNT RKSIRIGPGQAFYATGDIIGDIRQAHCNVSKATWNETLGK VVKQLRKHFGNNTIIRFANSSGGDLEVTTHSFNCGGEFFY CNTSGLFNSTWISNDSITLPCRIKQIINMWQRIGQAMYAP PIQGVIRCVSNITGLILTRDGGSTNSTTETFRPGGGDMRD NWRSELYKYKVVKIE J:  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX XXXXXXXXXXXXXXXXXXXXXXX K:  EIVLTQSPGTLSLSPGETASLSCTAASYGHMTWYQKKPGQ PPKLLIFATSKRASGIPDRFSGSQFGKQYTLTITRMEPED FARYYCQQLEFFGQGTRLEIRRTVAAPSVFIFPPSDEQLK SGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQ DSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVT KSFNRGEC L:  QVQLVQSGSGVKKPGASVRVSCWTSEDIFERTELIHWVRQ APGQGLEWIGWVKTVTGAVNFGSPDFRQRVSLTRDRDLFT AHMDIRGLTQGDTATYFCARQKFYTGGQGWYFDLWGRGTL IVVSSASTKGPSVFPLAPSSKSGGTAALGCLVKDYFPEPV TVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLG TQTYICNVNHKPSNTKVDKKVEPKS Description (1)  BG505 SOSIP gp120, PGV04 heavy chain Functional site 1) chain C residue 192-198 type prosite sequence YACEVTH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH source prosite : PS00290 2) chain D residue 194-200 type prosite sequence YICNVNH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH source prosite : PS00290

Display surface Download Links