|
|
eF-site ID
|
3j2p-C |
|
PDB Code
|
3j2p |
|
Chain
|
C |
|
|
|
|
Title
|
CryoEM structure of Dengue virus envelope protein heterotetramer |
|
Classification
|
VIRAL PROTEIN |
|
Compound
|
Envelope protein E |
|
Source
|
ORGANISM_COMMON: DENV-2; ORGANISM_SCIENTIFIC: Dengue virus 2; |
|
|
Sequence
|
C: |
MRCIGISNRDFVEGVSGGSWVDIVLEHGSCVTTMAKNKPT
LDFELIETEAKQPATLRKYCIEAKLTNTTTDSRCPTQGEP
SLNEEQDKRFVCKHSMVDRGWGNGCGLFGKGGIVTCAMFT
CKKNMKGKVVQPENLEYTIVITPHSGEEHAVGNDTGKHGK
EIKITPQSSITEAELTGYGTVTMECSPRTGLDFNEMVLLQ
MENKAWLVHRQWFLDLPLPWLPGADTQGSNWIQKETLVTF
KNPHAKKQDVVVLGSQEGAMHTALTGATEIQMSSGNLLFT
GHLKCRLRMDKLQLKGMSYSMCTGKFKVVKEIAETQHGTI
VIRVQYEGDGSPCKIPFEIMDLEKRHVLGRLITVNPIVTE
KDSPVNIEAEPPFGDSYIIIGVEPGQLKLNWFKKGSSIGQ
MIETTMRGAKRMAILGDTAWDFGSLGGVFTSIGKALHQVF
GAIYGAAFSGVSWIMKILIGVIITWIGMNSRSTSLSVSLV
LVGVVTLYLGVMVQA
|
|
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Description
|
(1) |
Envelope protein E, Small envelope protein M
|
|
Functional site
|
|
|
1)
|
chain |
C |
| residue |
446-466 |
| type |
TOPO_DOM |
| sequence |
AAFSGVSWIMKILIGVIITWI
|
| description |
Cytoplasmic => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
2)
|
chain |
C |
| residue |
473-493 |
| type |
TOPO_DOM |
| sequence |
TSLSVSLVLVGVVTLYLGVMV
|
| description |
Cytoplasmic => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
C |
| residue |
495 |
| type |
SITE |
| sequence |
A
|
| description |
Cleavage; by host signal peptidase => ECO:0000269|PubMed:2952760
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
4)
|
chain |
C |
| residue |
67 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine; by host => ECO:0000255|PROSITE-ProRule:PRU00498
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
5)
|
chain |
C |
| residue |
153 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine; by host => ECO:0000255|PROSITE-ProRule:PRU00498
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
|