eF-site ID 3j25-A PDB Code 3j25 Chain A click to enlarge Title Structural basis for TetM-mediated tetracycline resistance Classification TRANSLATION Compound Tetracycline resistance protein tetM Source (TET1_ENTFL) Sequence A:  KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTT RTDNTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDF LAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELY PNVCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELE QEESIRFQNCSLFPLYHGSAKSNIGIDNLIEVITNKFYSS THRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLHLRDSV RVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFL KLNSVLGDTKLLPQRKKIENPHPLLQTTVEPSKPEQREML LDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQMEVISA LLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPF WASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGI RYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAP IVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKY CANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRS VCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT Description Functional site 1) chain A residue 13 type sequence D description BINDING SITE FOR RESIDUE GCP A 701 source : AC1 2) chain A residue 14 type sequence A description BINDING SITE FOR RESIDUE GCP A 701 source : AC1 3) chain A residue 15 type sequence G description BINDING SITE FOR RESIDUE GCP A 701 source : AC1 4) chain A residue 16 type sequence K description BINDING SITE FOR RESIDUE GCP A 701 source : AC1 5) chain A residue 17 type sequence T description BINDING SITE FOR RESIDUE GCP A 701 source : AC1 6) chain A residue 18 type sequence T description BINDING SITE FOR RESIDUE GCP A 701 source : AC1 7) chain A residue 19 type sequence L description BINDING SITE FOR RESIDUE GCP A 701 source : AC1 8) chain A residue 54 type sequence I description BINDING SITE FOR RESIDUE GCP A 701 source : AC1 9) chain A residue 77 type sequence G description BINDING SITE FOR RESIDUE GCP A 701 source : AC1 10) chain A residue 130 type sequence I description BINDING SITE FOR RESIDUE GCP A 701 source : AC1 11) chain A residue 221 type sequence A description BINDING SITE FOR RESIDUE GCP A 701 source : AC1 12) chain A residue 222 type sequence K description BINDING SITE FOR RESIDUE GCP A 701 source : AC1 13) chain A residue 44-59 type prosite sequence DNTLLERQRGITIQTG description G_TR_1 Translational (tr)-type guanine nucleotide-binding (G) domain signature. DNtllERqRGITIqtG source prosite : PS00301 14) chain A residue 10 type BINDING sequence A description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 15) chain A residue 74 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 16) chain A residue 128 type BINDING sequence N description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1

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