eF-site ID 3in7-C PDB Code 3in7 Chain C click to enlarge Title Crystal Structure of the Grb2 SH2 Domain in Complex with a Cyclopropyl-constrained Ac-pY-Q-N-NH2 Tripeptide Mimic Classification SIGNALING PROTEIN/PEPTIDE Compound Growth factor receptor-bound protein 2 Source Homo sapiens (Human) (GRB2_HUMAN) Sequence C:  MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGD FSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDY HRSTSVSRNQQIFLRDIEQV Description Functional site 1) chain C residue 67 type sequence R description BINDING SITE FOR RESIDUE AYQ C 1 source : AC2 2) chain C residue 86 type sequence R description BINDING SITE FOR RESIDUE AYQ C 1 source : AC2 3) chain C residue 88 type sequence S description BINDING SITE FOR RESIDUE AYQ C 1 source : AC2 4) chain C residue 90 type sequence S description BINDING SITE FOR RESIDUE AYQ C 1 source : AC2 5) chain C residue 96 type sequence S description BINDING SITE FOR RESIDUE AYQ C 1 source : AC2 6) chain C residue 107 type sequence H description BINDING SITE FOR RESIDUE AYQ C 1 source : AC2 7) chain C residue 108 type sequence F description BINDING SITE FOR RESIDUE AYQ C 1 source : AC2 8) chain C residue 109 type sequence K description BINDING SITE FOR RESIDUE AYQ C 1 source : AC2 9) chain C residue 120 type sequence L description BINDING SITE FOR RESIDUE AYQ C 1 source : AC2 10) chain C residue 121 type sequence W description BINDING SITE FOR RESIDUE AYQ C 1 source : AC2 11) chain C residue 109 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI1

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