eF-site ID 3ii0-D PDB Code 3ii0 Chain D click to enlarge Title Crystal structure of human Glutamate oxaloacetate transaminase 1 (GOT1) Classification TRANSFERASE Compound Aspartate aminotransferase, cytoplasmic Source null (AATC_HUMAN) Sequence D:  MQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLP VVKKVEQKIANDNSLNHEYLPILGLAEFRSCASRLALGDD SPALKEKRVGGVQSLGGTGALRIGADFLARWYNGTNNKNT PVYVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQ GFLNDLENAPEFSIVVLHACAHNPTGIDPTPEQWKQIASV MKHRFLFPFFDSAYQGFASGNLERDAWAIRYFVSEGFEFF CAQSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIV RITWSNPPAQGARIVASTLSNPELFEEWTGNVKTMADRIL TMRSELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVE YLVNEKHIYLLPSGRINVSGLTTKNLDYVATSIHEAVTKI AENLYFQ Description Functional site 1) chain D residue 71 type sequence Y description BINDING SITE FOR RESIDUE PLP A 1 source : AC1 2) chain D residue 71 type sequence Y description BINDING SITE FOR RESIDUE TAR A 435 source : AC2 3) chain D residue 293 type sequence R description BINDING SITE FOR RESIDUE TAR A 435 source : AC2 4) chain D residue 108 type sequence G description BINDING SITE FOR RESIDUE PLP D 4 source : BC8 5) chain D residue 109 type sequence G description BINDING SITE FOR RESIDUE PLP D 4 source : BC8 6) chain D residue 110 type sequence T description BINDING SITE FOR RESIDUE PLP D 4 source : BC8 7) chain D residue 141 type sequence W description BINDING SITE FOR RESIDUE PLP D 4 source : BC8 8) chain D residue 195 type sequence N description BINDING SITE FOR RESIDUE PLP D 4 source : BC8 9) chain D residue 223 type sequence D description BINDING SITE FOR RESIDUE PLP D 4 source : BC8 10) chain D residue 226 type sequence Y description BINDING SITE FOR RESIDUE PLP D 4 source : BC8 11) chain D residue 256 type sequence S description BINDING SITE FOR RESIDUE PLP D 4 source : BC8 12) chain D residue 258 type sequence S description BINDING SITE FOR RESIDUE PLP D 4 source : BC8 13) chain D residue 259 type sequence K description BINDING SITE FOR RESIDUE PLP D 4 source : BC8 14) chain D residue 267 type sequence R description BINDING SITE FOR RESIDUE PLP D 4 source : BC8 15) chain D residue 18 type sequence V description BINDING SITE FOR RESIDUE TAR D 435 source : BC9 16) chain D residue 19 type sequence F description BINDING SITE FOR RESIDUE TAR D 435 source : BC9 17) chain D residue 39 type sequence G description BINDING SITE FOR RESIDUE TAR D 435 source : BC9 18) chain D residue 141 type sequence W description BINDING SITE FOR RESIDUE TAR D 435 source : BC9 19) chain D residue 195 type sequence N description BINDING SITE FOR RESIDUE TAR D 435 source : BC9 20) chain D residue 226 type sequence Y description BINDING SITE FOR RESIDUE TAR D 435 source : BC9 21) chain D residue 259 type sequence K description BINDING SITE FOR RESIDUE TAR D 435 source : BC9 22) chain D residue 361 type sequence F description BINDING SITE FOR RESIDUE TAR D 435 source : BC9 23) chain D residue 387 type sequence R description BINDING SITE FOR RESIDUE TAR D 435 source : BC9 24) chain D residue 157 type sequence R description BINDING SITE FOR RESIDUE EDO D 6 source : CC1 25) chain D residue 158 type sequence S description BINDING SITE FOR RESIDUE EDO D 6 source : CC1 26) chain D residue 41 type sequence Y description BINDING SITE FOR RESIDUE EDO D 8 source : CC2 27) chain D residue 43 type sequence T description BINDING SITE FOR RESIDUE EDO D 8 source : CC2 28) chain D residue 49 type sequence W description BINDING SITE FOR RESIDUE EDO D 8 source : CC2 29) chain D residue 81 type sequence R description BINDING SITE FOR RESIDUE EDO D 9 source : CC3 30) chain D residue 85 type sequence S description BINDING SITE FOR RESIDUE EDO D 9 source : CC3 31) chain D residue 101 type sequence V description BINDING SITE FOR RESIDUE EDO D 9 source : CC3 32) chain D residue 259 type MOD_RES sequence K description N6-(pyridoxal phosphate)lysine => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 33) chain D residue 39 type BINDING sequence G description source Swiss-Prot : SWS_FT_FI1 34) chain D residue 141 type BINDING sequence W description source Swiss-Prot : SWS_FT_FI1 35) chain D residue 195 type BINDING sequence N description source Swiss-Prot : SWS_FT_FI1 36) chain D residue 387 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI1 37) chain D residue 149 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P13221 source Swiss-Prot : SWS_FT_FI2

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