eF-site ID 3ii0-C PDB Code 3ii0 Chain C click to enlarge Title Crystal structure of human Glutamate oxaloacetate transaminase 1 (GOT1) Classification TRANSFERASE Compound Aspartate aminotransferase, cytoplasmic Source null (AATC_HUMAN) Sequence C:  MQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLP VVKKVEQKIANDNSLNHEYLPILGLAEFRSCASRLALGDD SPALKEKRVGGVQSLGGTGALRIGADFLARWYNGTNNKNT PVYVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQ GFLNDLENAPEFSIVVLHACAHNPTGIDPTPEQWKQIASV MKHRFLFPFFDSAYQGFASGNLERDAWAIRYFVSEGFEFF CAQSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIV RITWSNPPAQGARIVASTLSNPELFEEWTGNVKTMADRIL TMRSELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVE YLVNEKHIYLLPSGRINVSGLTTKNLDYVATSIHEAVTKI AENLYFQ Description Functional site 1) chain C residue 71 type sequence Y description BINDING SITE FOR RESIDUE PLP B 2 source : AC6 2) chain C residue 71 type sequence Y description BINDING SITE FOR RESIDUE TAR B 435 source : AC7 3) chain C residue 293 type sequence R description BINDING SITE FOR RESIDUE TAR B 435 source : AC7 4) chain C residue 108 type sequence G description BINDING SITE FOR RESIDUE PLP C 3 source : BC2 5) chain C residue 109 type sequence G description BINDING SITE FOR RESIDUE PLP C 3 source : BC2 6) chain C residue 110 type sequence T description BINDING SITE FOR RESIDUE PLP C 3 source : BC2 7) chain C residue 141 type sequence W description BINDING SITE FOR RESIDUE PLP C 3 source : BC2 8) chain C residue 195 type sequence N description BINDING SITE FOR RESIDUE PLP C 3 source : BC2 9) chain C residue 223 type sequence D description BINDING SITE FOR RESIDUE PLP C 3 source : BC2 10) chain C residue 226 type sequence Y description BINDING SITE FOR RESIDUE PLP C 3 source : BC2 11) chain C residue 256 type sequence S description BINDING SITE FOR RESIDUE PLP C 3 source : BC2 12) chain C residue 258 type sequence S description BINDING SITE FOR RESIDUE PLP C 3 source : BC2 13) chain C residue 259 type sequence K description BINDING SITE FOR RESIDUE PLP C 3 source : BC2 14) chain C residue 267 type sequence R description BINDING SITE FOR RESIDUE PLP C 3 source : BC2 15) chain C residue 18 type sequence V description BINDING SITE FOR RESIDUE TAR C 435 source : BC3 16) chain C residue 19 type sequence F description BINDING SITE FOR RESIDUE TAR C 435 source : BC3 17) chain C residue 38 type sequence V description BINDING SITE FOR RESIDUE TAR C 435 source : BC3 18) chain C residue 39 type sequence G description BINDING SITE FOR RESIDUE TAR C 435 source : BC3 19) chain C residue 141 type sequence W description BINDING SITE FOR RESIDUE TAR C 435 source : BC3 20) chain C residue 195 type sequence N description BINDING SITE FOR RESIDUE TAR C 435 source : BC3 21) chain C residue 226 type sequence Y description BINDING SITE FOR RESIDUE TAR C 435 source : BC3 22) chain C residue 259 type sequence K description BINDING SITE FOR RESIDUE TAR C 435 source : BC3 23) chain C residue 361 type sequence F description BINDING SITE FOR RESIDUE TAR C 435 source : BC3 24) chain C residue 387 type sequence R description BINDING SITE FOR RESIDUE TAR C 435 source : BC3 25) chain C residue 124 type sequence Y description BINDING SITE FOR RESIDUE EDO C 5 source : BC4 26) chain C residue 125 type sequence N description BINDING SITE FOR RESIDUE EDO C 5 source : BC4 27) chain C residue 157 type sequence R description BINDING SITE FOR RESIDUE EDO C 7 source : BC5 28) chain C residue 158 type sequence S description BINDING SITE FOR RESIDUE EDO C 7 source : BC5 29) chain C residue 41 type sequence Y description BINDING SITE FOR RESIDUE EDO C 12 source : BC6 30) chain C residue 326 type sequence T description BINDING SITE FOR RESIDUE EDO C 12 source : BC6 31) chain C residue 81 type sequence R description BINDING SITE FOR RESIDUE EDO C 436 source : BC7 32) chain C residue 103 type sequence G description BINDING SITE FOR RESIDUE EDO C 436 source : BC7 33) chain C residue 259 type MOD_RES sequence K description N6-(pyridoxal phosphate)lysine => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 34) chain C residue 141 type BINDING sequence W description source Swiss-Prot : SWS_FT_FI1 35) chain C residue 195 type BINDING sequence N description source Swiss-Prot : SWS_FT_FI1 36) chain C residue 387 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI1 37) chain C residue 39 type BINDING sequence G description source Swiss-Prot : SWS_FT_FI1 38) chain C residue 149 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P13221 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links