eF-site ID 3ii0-B PDB Code 3ii0 Chain B click to enlarge Title Crystal structure of human Glutamate oxaloacetate transaminase 1 (GOT1) Classification TRANSFERASE Compound Aspartate aminotransferase, cytoplasmic Source null (AATC_HUMAN) Sequence B:  PVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVV KKVEQKIANDNSLNHEYLPILGLAEFRSCASRLALGDDSP ALKEKRVGGVQSLGGTGALRIGADFLARWYNGTNNKNTPV YVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGF LNDLENAPEFSIVVLHACAHNPTGIDPTPEQWKQIASVMK HRFLFPFFDSAYQGFASGNLERDAWAIRYFVSEGFEFFCA QSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIVRI TWSNPPAQGARIVASTLSNPELFEEWTGNVKTMADRILTM RSELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVEYL VNEKHIYLLPSGRINVSGLTTKNLDYVATSIHEAVTKIAE NLYFQ Description Functional site 1) chain B residue 108 type sequence G description BINDING SITE FOR RESIDUE PLP B 2 source : AC6 2) chain B residue 109 type sequence G description BINDING SITE FOR RESIDUE PLP B 2 source : AC6 3) chain B residue 110 type sequence T description BINDING SITE FOR RESIDUE PLP B 2 source : AC6 4) chain B residue 141 type sequence W description BINDING SITE FOR RESIDUE PLP B 2 source : AC6 5) chain B residue 195 type sequence N description BINDING SITE FOR RESIDUE PLP B 2 source : AC6 6) chain B residue 223 type sequence D description BINDING SITE FOR RESIDUE PLP B 2 source : AC6 7) chain B residue 225 type sequence A description BINDING SITE FOR RESIDUE PLP B 2 source : AC6 8) chain B residue 226 type sequence Y description BINDING SITE FOR RESIDUE PLP B 2 source : AC6 9) chain B residue 256 type sequence S description BINDING SITE FOR RESIDUE PLP B 2 source : AC6 10) chain B residue 258 type sequence S description BINDING SITE FOR RESIDUE PLP B 2 source : AC6 11) chain B residue 259 type sequence K description BINDING SITE FOR RESIDUE PLP B 2 source : AC6 12) chain B residue 267 type sequence R description BINDING SITE FOR RESIDUE PLP B 2 source : AC6 13) chain B residue 18 type sequence V description BINDING SITE FOR RESIDUE TAR B 435 source : AC7 14) chain B residue 19 type sequence F description BINDING SITE FOR RESIDUE TAR B 435 source : AC7 15) chain B residue 38 type sequence V description BINDING SITE FOR RESIDUE TAR B 435 source : AC7 16) chain B residue 39 type sequence G description BINDING SITE FOR RESIDUE TAR B 435 source : AC7 17) chain B residue 141 type sequence W description BINDING SITE FOR RESIDUE TAR B 435 source : AC7 18) chain B residue 195 type sequence N description BINDING SITE FOR RESIDUE TAR B 435 source : AC7 19) chain B residue 226 type sequence Y description BINDING SITE FOR RESIDUE TAR B 435 source : AC7 20) chain B residue 259 type sequence K description BINDING SITE FOR RESIDUE TAR B 435 source : AC7 21) chain B residue 387 type sequence R description BINDING SITE FOR RESIDUE TAR B 435 source : AC7 22) chain B residue 41 type sequence Y description BINDING SITE FOR RESIDUE EDO B 1 source : AC8 23) chain B residue 43 type sequence T description BINDING SITE FOR RESIDUE EDO B 1 source : AC8 24) chain B residue 49 type sequence W description BINDING SITE FOR RESIDUE EDO B 1 source : AC8 25) chain B residue 128 type sequence N description BINDING SITE FOR RESIDUE EDO B 10 source : AC9 26) chain B residue 130 type sequence K description BINDING SITE FOR RESIDUE EDO B 10 source : AC9 27) chain B residue 78 type sequence A description BINDING SITE FOR RESIDUE EDO B 436 source : BC1 28) chain B residue 81 type sequence R description BINDING SITE FOR RESIDUE EDO B 436 source : BC1 29) chain B residue 82 type sequence S description BINDING SITE FOR RESIDUE EDO B 436 source : BC1 30) chain B residue 103 type sequence G description BINDING SITE FOR RESIDUE EDO B 436 source : BC1 31) chain B residue 71 type sequence Y description BINDING SITE FOR RESIDUE PLP C 3 source : BC2 32) chain B residue 71 type sequence Y description BINDING SITE FOR RESIDUE TAR C 435 source : BC3 33) chain B residue 293 type sequence R description BINDING SITE FOR RESIDUE TAR C 435 source : BC3 34) chain B residue 259 type MOD_RES sequence K description N6-(pyridoxal phosphate)lysine => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 35) chain B residue 39 type BINDING sequence G description source Swiss-Prot : SWS_FT_FI1 36) chain B residue 141 type BINDING sequence W description source Swiss-Prot : SWS_FT_FI1 37) chain B residue 195 type BINDING sequence N description source Swiss-Prot : SWS_FT_FI1 38) chain B residue 387 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI1 39) chain B residue 149 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P13221 source Swiss-Prot : SWS_FT_FI2

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