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Functional site
| 1) | chain | A |
| residue | 333 | |
| type | ||
| sequence | N | |
| description | BINDING SITE FOR RESIDUE NEH C 76 | |
| source | : AC1 | |
| 2) | chain | A |
| residue | 335 | |
| type | ||
| sequence | C | |
| description | BINDING SITE FOR RESIDUE NEH C 76 | |
| source | : AC1 | |
| 3) | chain | A |
| residue | 433 | |
| type | ||
| sequence | Q | |
| description | BINDING SITE FOR RESIDUE NEH C 76 | |
| source | : AC1 | |
| 4) | chain | A |
| residue | 794 | |
| type | ||
| sequence | G | |
| description | BINDING SITE FOR RESIDUE NEH C 76 | |
| source | : AC1 | |
| 5) | chain | A |
| residue | 199 | |
| type | ||
| sequence | C | |
| description | BINDING SITE FOR RESIDUE ZN A 836 | |
| source | : AC4 | |
| 6) | chain | A |
| residue | 202 | |
| type | ||
| sequence | C | |
| description | BINDING SITE FOR RESIDUE ZN A 836 | |
| source | : AC4 | |
| 7) | chain | A |
| residue | 219 | |
| type | ||
| sequence | C | |
| description | BINDING SITE FOR RESIDUE ZN A 836 | |
| source | : AC4 | |
| 8) | chain | A |
| residue | 232 | |
| type | ||
| sequence | H | |
| description | BINDING SITE FOR RESIDUE ZN A 836 | |
| source | : AC4 | |
| 9) | chain | A |
| residue | 327-342 | |
| type | prosite | |
| sequence | GIRNLGNSCYLNSVVQ | |
| description | USP_1 Ubiquitin specific protease (USP) domain signature 1. GIrnlGNsCYLNSvVQ | |
| source | prosite : PS00972 | |
| 10) | chain | A |
| residue | 778-796 | |
| type | prosite | |
| sequence | YQLFAFISHMGTSTMCGHY | |
| description | USP_2 Ubiquitin specific protease (USP) domain signature 2. YqLfAFisHmGtstmc.GHY | |
| source | prosite : PS00973 | |
| 11) | chain | A |
| residue | 175-283 | |
| type | ZN_FING | |
| sequence |
QVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTD GSILCGRRYDGSGGNNHAVEHYRETGYPLAVKLGTITPDG ADVYSYDEDDMVLDPSLAEHLSHFGIDM |
|
| description | UBP-type; degenerate => ECO:0000255|PROSITE-ProRule:PRU00502 | |
| source | Swiss-Prot : SWS_FT_FI1 | |
| 12) | chain | A |
| residue | 779 | |
| type | MOD_RES | |
| sequence | Q | |
| description | Phosphoserine => ECO:0007744|PubMed:23186163 | |
| source | Swiss-Prot : SWS_FT_FI10 | |
| 13) | chain | A |
| residue | 785 | |
| type | MOD_RES | |
| sequence | S | |
| description | Phosphoserine => ECO:0007744|PubMed:23186163 | |
| source | Swiss-Prot : SWS_FT_FI10 | |
| 14) | chain | A |
| residue | 783 | |
| type | MOD_RES | |
| sequence | F | |
| description | Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163 | |
| source | Swiss-Prot : SWS_FT_FI11 | |
| 15) | chain | A |
| residue | 335 | |
| type | ACT_SITE | |
| sequence | C | |
| description | Nucleophile | |
| source | Swiss-Prot : SWS_FT_FI2 | |
| 16) | chain | A |
| residue | 818 | |
| type | ACT_SITE | |
| sequence | E | |
| description | Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10092, ECO:0000255|PROSITE-ProRule:PRU10093 | |
| source | Swiss-Prot : SWS_FT_FI3 | |
| 17) | chain | A |
| residue | 199 | |
| type | BINDING | |
| sequence | C | |
| description | BINDING => ECO:0000255|PROSITE-ProRule:PRU00502 | |
| source | Swiss-Prot : SWS_FT_FI4 | |
| 18) | chain | A |
| residue | 202 | |
| type | BINDING | |
| sequence | C | |
| description | BINDING => ECO:0000255|PROSITE-ProRule:PRU00502 | |
| source | Swiss-Prot : SWS_FT_FI4 | |
| 19) | chain | A |
| residue | 219 | |
| type | BINDING | |
| sequence | C | |
| description | BINDING => ECO:0000255|PROSITE-ProRule:PRU00502 | |
| source | Swiss-Prot : SWS_FT_FI4 | |
| 20) | chain | A |
| residue | 232 | |
| type | BINDING | |
| sequence | H | |
| description | BINDING => ECO:0000255|PROSITE-ProRule:PRU00502 | |
| source | Swiss-Prot : SWS_FT_FI4 | |
| 21) | chain | A |
| residue | 209 | |
| type | BINDING | |
| sequence | W | |
| description | ||
| source | Swiss-Prot : SWS_FT_FI5 | |
| 22) | chain | A |
| residue | 221 | |
| type | BINDING | |
| sequence | R | |
| description | ||
| source | Swiss-Prot : SWS_FT_FI5 | |
| 23) | chain | A |
| residue | 259 | |
| type | BINDING | |
| sequence | Y | |
| description | ||
| source | Swiss-Prot : SWS_FT_FI5 | |
| 24) | chain | A |
| residue | 261 | |
| type | BINDING | |
| sequence | Y | |
| description | ||
| source | Swiss-Prot : SWS_FT_FI5 | |
| 25) | chain | A |
| residue | 264 | |
| type | BINDING | |
| sequence | D | |
| description | ||
| source | Swiss-Prot : SWS_FT_FI5 | |
| 26) | chain | A |
| residue | 2 | |
| type | MOD_RES | |
| sequence | A | |
| description | N-acetylalanine => ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378 | |
| source | Swiss-Prot : SWS_FT_FI6 | |
| 27) | chain | A |
| residue | 156 | |
| type | MOD_RES | |
| sequence | S | |
| description | Phosphoserine => ECO:0007744|PubMed:24275569 | |
| source | Swiss-Prot : SWS_FT_FI7 | |