|
|
eF-site ID
|
3i89-AB |
|
PDB Code
|
3i89 |
|
Chain
|
A, B |
|
click to enlarge
|
|
|
Title
|
Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR22 |
|
Classification
|
PROTEIN BINDING |
|
Compound
|
DNA damage-binding protein 1 |
|
Source
|
Homo sapiens (Human) (WDR22_HUMAN) |
|
|
Sequence
|
A: |
MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLE
IYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFIL
TAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGI
IGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLE
ELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREK
EFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYH
NGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRL
FMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNG
VVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIV
DMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHA
SIDLPGIKGLWPLRSDPNRETYDTLVLSFVGQTRVLMLNG
EEVEETELMGFVDDQQTFFCGNVAHQQLIQITSASVRLVS
QEPKALVSEWKEPQAKNISVASCNSSQVVVAVGRALYYLQ
IHPQELRQISHTEMEHEVACLDITPLGDSNGLSPLCAIGL
WTDISARILKLPSFELLHKEMLGGEIIPRSILMTTFESSH
YLLCALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRT
FRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMC
PLNSDGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLYES
PRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRPSASTQA
LSSSVSSSKLFSSGEEVEVHNLLIIDQHTFEVLHAHQFLQ
NEYALSLVSCKLGKDPNTYFIVGTAMVYPEEAEPKQGRIV
VFQYSDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVR
LYEWTTEKDVRTECNHYNNIMALYLKTKGDFILVGDLMRS
VLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAE
NAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCH
GSLVMQPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDMQN
RLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIES
FLDISRPKMQEVVANREATADDLIKVVEELTRIH
|
| B: |
SVVGFLSQRGLHG
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
2 |
| type |
MOD_RES |
| sequence |
S
|
| description |
N-acetylserine => ECO:0007744|PubMed:19413330
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
A |
| residue |
1067 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
A |
| residue |
1125 |
| type |
MOD_RES |
| sequence |
T
|
| description |
Phosphothreonine => ECO:0000250|UniProtKB:Q9ESW0
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|