eF-site ID 3i4n-B PDB Code 3i4n Chain B click to enlarge Title 8-oxoguanine containing RNA polymerase II elongation complex E Classification TRANSCRIPTION,TRANSFERASE/DNA-RNA HYBRID Compound DNA-directed RNA polymerase II subunit RPB1 Source ORGANISM_COMMON: baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; Sequence B:  DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTL QDIICEDSTLIISFGKIYVTKPMVNESDGVTHALYPQEAR LRNLTYSSGLFVDVKKRTYEKVFIGRLPIMLRSKNCYLSE ATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIV QVFKKAAPSPISHVAEIRSALEKGSRFISTLQVKLYGREG SSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICY DVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTALGI KKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMIN RLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKK LTKDIFRYMQRTVELAINAKTITSGLKYALATGNWGEQKK AMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKP RQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDP MPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHR NPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAG RVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDEYT WSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEADVDPA KRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPR NTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTT RAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSI DRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMK HGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPISSKRDAST PLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDK FASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPS RMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLL REHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMV DDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMI AHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQ FECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTD RSRDF Description Functional site 1) chain B residue 1163 type sequence C description BINDING SITE FOR RESIDUE ZN B 2225 source : AC4 2) chain B residue 1166 type sequence C description BINDING SITE FOR RESIDUE ZN B 2225 source : AC4 3) chain B residue 1182 type sequence C description BINDING SITE FOR RESIDUE ZN B 2225 source : AC4 4) chain B residue 1185 type sequence C description BINDING SITE FOR RESIDUE ZN B 2225 source : AC4 5) chain B residue 977-989 type prosite sequence GDKFASRHGQKGT description RNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT source prosite : PS01166 6) chain B residue 919 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956 source Swiss-Prot : SWS_FT_FI3 7) chain B residue 1185 type MOD_RES sequence C description Phosphothreonine => ECO:0007744|PubMed:19779198 source Swiss-Prot : SWS_FT_FI2 8) chain B residue 1182 type MOD_RES sequence C description Phosphothreonine => ECO:0007744|PubMed:19779198 source Swiss-Prot : SWS_FT_FI2 9) chain B residue 1166 type MOD_RES sequence C description Phosphothreonine => ECO:0007744|PubMed:19779198 source Swiss-Prot : SWS_FT_FI2 10) chain B residue 837 type catalytic sequence D description 788 source MCSA : MCSA1

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