eF-site ID 3hvl-B PDB Code 3hvl Chain B click to enlarge Title Tethered PXR-LBD/SRC-1p complexed with SR-12813 Classification Transcription, Transferase Compound Pregnane X receptor, Linker, Steroid receptor coactivator 1 Source Homo sapiens (Human) (NCOA1_HUMAN) Sequence B:  VQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLS REEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSG GKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQ ISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEQLL LEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQH RVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTE LRSINAQHTQRLLRIQDIHPFATPLMQELFGISLTERHKI LHRLLQEGS Description Functional site 1) chain B residue 244 type sequence A description BINDING SITE FOR RESIDUE SRL B 2 source : AC2 2) chain B residue 247 type sequence S description BINDING SITE FOR RESIDUE SRL B 2 source : AC2 3) chain B residue 251 type sequence F description BINDING SITE FOR RESIDUE SRL B 2 source : AC2 4) chain B residue 281 type sequence F description BINDING SITE FOR RESIDUE SRL B 2 source : AC2 5) chain B residue 285 type sequence Q description BINDING SITE FOR RESIDUE SRL B 2 source : AC2 6) chain B residue 299 type sequence W description BINDING SITE FOR RESIDUE SRL B 2 source : AC2 7) chain B residue 306 type sequence Y description BINDING SITE FOR RESIDUE SRL B 2 source : AC2 8) chain B residue 323 type sequence M description BINDING SITE FOR RESIDUE SRL B 2 source : AC2 9) chain B residue 327 type sequence H description BINDING SITE FOR RESIDUE SRL B 2 source : AC2 10) chain B residue 407 type sequence H description BINDING SITE FOR RESIDUE SRL B 2 source : AC2 11) chain B residue 411 type sequence L description BINDING SITE FOR RESIDUE SRL B 2 source : AC2 12) chain B residue 420 type sequence F description BINDING SITE FOR RESIDUE SRL B 2 source : AC2 13) chain B residue 429 type sequence F description BINDING SITE FOR RESIDUE SRL B 2 source : AC2 14) chain B residue 247 type BINDING sequence S description BINDING => ECO:0000269|PubMed:12578355, ECO:0007744|PDB:1M13 source Swiss-Prot : SWS_FT_FI1 15) chain B residue 285 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:12578355, ECO:0007744|PDB:1M13 source Swiss-Prot : SWS_FT_FI1 16) chain B residue 407 type BINDING sequence H description BINDING => ECO:0000269|PubMed:12578355, ECO:0007744|PDB:1M13 source Swiss-Prot : SWS_FT_FI1 17) chain B residue 460 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI2

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