eF-site ID 3hvl-A PDB Code 3hvl Chain A click to enlarge Title Tethered PXR-LBD/SRC-1p complexed with SR-12813 Classification Transcription, Transferase Compound Pregnane X receptor, Linker, Steroid receptor coactivator 1 Source Homo sapiens (Human) (NCOA1_HUMAN) Sequence A:  GLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSRE EAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGK EIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQIS LLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEQQLLL EPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHR VVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTEL RSINAQHTQRLLRIQDIHPFATPLMQELFGITSLTERHKI LHRLLQE Description Functional site 1) chain A residue 243 type sequence M description BINDING SITE FOR RESIDUE SRL A 1 source : AC1 2) chain A residue 246 type sequence M description BINDING SITE FOR RESIDUE SRL A 1 source : AC1 3) chain A residue 247 type sequence S description BINDING SITE FOR RESIDUE SRL A 1 source : AC1 4) chain A residue 251 type sequence F description BINDING SITE FOR RESIDUE SRL A 1 source : AC1 5) chain A residue 281 type sequence F description BINDING SITE FOR RESIDUE SRL A 1 source : AC1 6) chain A residue 285 type sequence Q description BINDING SITE FOR RESIDUE SRL A 1 source : AC1 7) chain A residue 288 type sequence F description BINDING SITE FOR RESIDUE SRL A 1 source : AC1 8) chain A residue 299 type sequence W description BINDING SITE FOR RESIDUE SRL A 1 source : AC1 9) chain A residue 306 type sequence Y description BINDING SITE FOR RESIDUE SRL A 1 source : AC1 10) chain A residue 323 type sequence M description BINDING SITE FOR RESIDUE SRL A 1 source : AC1 11) chain A residue 407 type sequence H description BINDING SITE FOR RESIDUE SRL A 1 source : AC1 12) chain A residue 411 type sequence L description BINDING SITE FOR RESIDUE SRL A 1 source : AC1 13) chain A residue 420 type sequence F description BINDING SITE FOR RESIDUE SRL A 1 source : AC1 14) chain A residue 425 type sequence M description BINDING SITE FOR RESIDUE SRL A 1 source : AC1 15) chain A residue 429 type sequence F description BINDING SITE FOR RESIDUE SRL A 1 source : AC1 16) chain A residue 247 type BINDING sequence S description BINDING => ECO:0000269|PubMed:12578355, ECO:0007744|PDB:1M13 source Swiss-Prot : SWS_FT_FI1 17) chain A residue 285 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:12578355, ECO:0007744|PDB:1M13 source Swiss-Prot : SWS_FT_FI1 18) chain A residue 407 type BINDING sequence H description BINDING => ECO:0000269|PubMed:12578355, ECO:0007744|PDB:1M13 source Swiss-Prot : SWS_FT_FI1

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