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Title
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Ligand recognition by A-class EPH receptors: crystal structures of the EPHA2 ligand-binding domain and the EPHA2/EPHRIN-A1 complex |
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Classification
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TRANSFERASE |
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Compound
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Ephrin type-A receptor 2 |
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Source
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Homo sapiens (Human) (EPHA2_HUMAN) |
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Sequence
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A: |
EVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDMPIYMY
SVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNS
FPGGASSCKETFNLYYAESDLDYGTNFQKRLFTKIDTIAP
DEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGA
CVALLSVRVYYKKC
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| B: |
EVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDMPIYMY
SVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNS
FPGGASSCKETFNLYYAESDLDYGTNFQKRLFTKIDTIAP
DEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGA
CVALLSVRVYYKKC
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| C: |
EVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDMPIYMY
SVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNS
FPGGASSCKETFNLYYAESDLDYGTNFQKRLFTKIDTIAP
DEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGA
CVALLSVRVYYKKC
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| D: |
EVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDMPIYMY
SVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNS
FPGGASSCKETFNLYYAESDLDYGTNFQKRLFTKIDTIAP
DEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGA
CVALLSVRVYYKKC
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| E: |
EVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDMPIYMY
SVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNS
FPGGASSCKETFNLYYAESDLDYGTNFQKRLFTKIDTIAP
DEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGA
CVALLSVRVYYKKC
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| F: |
EVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDMPIYMY
SVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNS
FPGGASSCKETFNLYYAESDLDYGTNFQKRLFTKIDTIAP
DEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGA
CVALLSVRVYYKKC
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Description
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