eF-site ID 3hha-B PDB Code 3hha Chain B click to enlarge Title Crystal structure of cathepsin L in complex with AZ12878478 Classification HYDROLASE Compound Cathepsin L1 Source Homo sapiens (Human) (CATL1_HUMAN) Sequence B:  APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFR KTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDN GGLDSEESYPYEATEESCKYNPKYSVANDAGFVDIPKQEK ALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSED MDHGVLVVGYGFESTNKYWLVKNSWGEEWGMGGYVKMAKD RRNHCGIASAASYPTV Description Functional site 1) chain B residue 19 type sequence Q description BINDING SITE FOR RESIDUE NOW B 301 source : AC4 2) chain B residue 23 type sequence G description BINDING SITE FOR RESIDUE NOW B 301 source : AC4 3) chain B residue 24 type sequence S description BINDING SITE FOR RESIDUE NOW B 301 source : AC4 4) chain B residue 25 type sequence C description BINDING SITE FOR RESIDUE NOW B 301 source : AC4 5) chain B residue 26 type sequence W description BINDING SITE FOR RESIDUE NOW B 301 source : AC4 6) chain B residue 61 type sequence G description BINDING SITE FOR RESIDUE NOW B 301 source : AC4 7) chain B residue 63 type sequence E description BINDING SITE FOR RESIDUE NOW B 301 source : AC4 8) chain B residue 67 type sequence G description BINDING SITE FOR RESIDUE NOW B 301 source : AC4 9) chain B residue 68 type sequence G description BINDING SITE FOR RESIDUE NOW B 301 source : AC4 10) chain B residue 69 type sequence L description BINDING SITE FOR RESIDUE NOW B 301 source : AC4 11) chain B residue 135 type sequence A description BINDING SITE FOR RESIDUE NOW B 301 source : AC4 12) chain B residue 161 type sequence M description BINDING SITE FOR RESIDUE NOW B 301 source : AC4 13) chain B residue 162 type sequence D description BINDING SITE FOR RESIDUE NOW B 301 source : AC4 14) chain B residue 19 type sequence Q description BINDING SITE FOR RESIDUE PGE B 221 source : AC5 15) chain B residue 20 type sequence G description BINDING SITE FOR RESIDUE PGE B 221 source : AC5 16) chain B residue 22 type sequence C description BINDING SITE FOR RESIDUE PGE B 221 source : AC5 17) chain B residue 23 type sequence G description BINDING SITE FOR RESIDUE PGE B 221 source : AC5 18) chain B residue 144 type sequence L description BINDING SITE FOR RESIDUE PGE B 221 source : AC5 19) chain B residue 189 type sequence W description BINDING SITE FOR RESIDUE PGE B 221 source : AC5 20) chain B residue 108 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:12754519, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218 source Swiss-Prot : SWS_FT_FI3 21) chain B residue 25 type ACT_SITE sequence C description ACT_SITE => ECO:0000305|PubMed:9468501 source Swiss-Prot : SWS_FT_FI1 22) chain B residue 187 type ACT_SITE sequence N description source Swiss-Prot : SWS_FT_FI2 23) chain B residue 163 type ACT_SITE sequence H description source Swiss-Prot : SWS_FT_FI2

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