|
|
eF-site ID
|
3hg1-E |
|
PDB Code
|
3hg1 |
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Chain
|
E |
|
click to enlarge
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Title
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Germline-governed recognition of a cancer epitope by an immunodominant human T cell receptor |
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Classification
|
IMMUNE SYSTEM |
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Compound
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MHC class I antigen |
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Source
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ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: HOMO SAPIENS; |
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Sequence
|
E: |
SQTIHQWPATLVQPVGSPLSLECTVEGTSNPNLYWYRQAA
GRGLQLLFYSVGIGQISSEVPQNLSASRPQDRQFILSSKK
LLLSDSGFYLCAWSETGLGTGELFFGEGSRLTVLEDLKNV
FPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWW
VNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATF
WQDPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAW
GRAD
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Description
|
(1) |
MHC class I antigen, Beta-2-microglobulin, CANCER/MART-1, T-CELL RECEPTOR, ALPHA CHAIN, T-cell Receptor, Beta Chain
|
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Functional site
|
|
|
1)
|
chain |
E |
| residue |
13 |
| type |
|
| sequence |
Q
|
| description |
BINDING SITE FOR RESIDUE GOL E 802
|
| source |
: AC4
|
|
|
2)
|
chain |
E |
| residue |
14 |
| type |
|
| sequence |
P
|
| description |
BINDING SITE FOR RESIDUE GOL E 802
|
| source |
: AC4
|
|
|
3)
|
chain |
E |
| residue |
219 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR RESIDUE GOL E 802
|
| source |
: AC4
|
|
|
4)
|
chain |
E |
| residue |
220 |
| type |
|
| sequence |
N
|
| description |
BINDING SITE FOR RESIDUE GOL E 802
|
| source |
: AC4
|
|
|
5)
|
chain |
E |
| residue |
184 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498
|
| source |
Swiss-Prot : SWS_FT_FI1
|
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