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eF-site ID
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3hei-B |
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PDB Code
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3hei |
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Chain
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B |
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click to enlarge
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Title
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Ligand Recognition by A-Class Eph Receptors: Crystal Structures of the EphA2 Ligand-Binding Domain and the EphA2/ephrin-A1 Complex |
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Classification
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TRANSFERASE/SIGNALING PROTEIN |
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Compound
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Ephrin type-A receptor 2 |
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Source
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Homo sapiens (Human) (EFNA1_HUMAN) |
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Sequence
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B: |
ADRHTVFWNSSNPKFRNEDYTIHVQLNDYVDIICPHYEDH
SVADAAMEQYILYLVEHEEYQLCQPQSKDQVRWQCNRPSA
KHGPEKLSEKFQRFTPFTLGKEFKEGHSYYYISKPIHQHE
DRCLRLKVTVKI
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Description
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(1) |
Ephrin type-A receptor 2 (E.C.2.7.10.1), Ephrin-A1
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Functional site
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1)
|
chain |
B |
| residue |
103-130 |
| type |
prosite |
| sequence |
KLSEKFQRFTPFTLGKEFKEGHSYYYIS
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| description |
EPHRIN_RBD_1 Ephrin receptor-binding (ephrin RBD) domain signature. KLSeKFQrFTPftlGkEFkeghsYYyiS
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| source |
prosite : PS01299
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2)
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chain |
B |
| residue |
26 |
| type |
CARBOHYD |
| sequence |
N
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| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:20505120, ECO:0000269|PubMed:23661698
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| source |
Swiss-Prot : SWS_FT_FI1
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