eF-site ID 3hc0-ABHL PDB Code 3hc0 Chain A, B, H, L click to enlarge Title BHA10 IgG1 wild-type Fab - antibody directed at human LTBR Classification IMMUNE SYSTEM Compound IMMUNOGLOBULIN IGG1 FAB, LIGHT CHAIN Source (3HC0) Sequence A:  QVQLVQSGAEVKKPGSSVKVSCKASGYTFTTYYLHWVRQA PGQGLEWMGWIYPGNVHAQYNEKFKGRVTITADKSTSTAY MELSSLRSEDTAVYYCARSWEGFPYWGQGTTVTVSSASTK GPSVFPLAPGTAALGCLVKDYFPEPVTVSWNSGALTSGVH TFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSN TKVDKKVEP B:  DIQMTQSPSSLSASVGDRVTITCKASQNVGINVAWYQQKP GKAPKSLISSASYRYSGVPSRFSGSGSGTDFTLTISSLQP EDFATYFCQQYDTYPFTFGQGTKVEIKRTVAAPSVFIFPP SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQG LSSPVTKSFNRGE H:  QVQLVQSGAEVKKPGSSVKVSCKASGYTFTTYYLHWVRQA PGQGLEWMGWIYPGNVHAQYNEKFKGRVTITADKSTSTAY MELSSLRSEDTAVYYCARSWEGFPYWGQGTTVTVSSASTK GPSVFPLAPSSGGTAALGCLVKDYFPEPVTVSWNSGALTS GVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHK PSNTKVDKKVEPK L:  DIQMTQSPSSLSASVGDRVTITCKASQNVGINVAWYQQKP GKAPKSLISSASYRYSGVPSRFSGSGSGTDFTLTISSLQP EDFATYFCQQYDTYPFTFGQGTKVEIKRTVAAPSVFIFPP SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQG LSSPVTKSFNRG Description (1)  IMMUNOGLOBULIN IGG1 FAB, LIGHT CHAIN, IMMUNOGLOBULIN IGG1 FAB, HEAVY CHAIN Functional site 1) chain H residue 33 type sequence Y description BINDING SITE FOR RESIDUE ACT H 702 source : AC1 2) chain H residue 35 type sequence H description BINDING SITE FOR RESIDUE ACT H 702 source : AC1 3) chain H residue 50 type sequence W description BINDING SITE FOR RESIDUE ACT H 702 source : AC1 4) chain H residue 99 type sequence S description BINDING SITE FOR RESIDUE ACT H 702 source : AC1 5) chain L residue 94 type sequence Y description BINDING SITE FOR RESIDUE ACT H 702 source : AC1 6) chain A residue 33 type sequence Y description BINDING SITE FOR RESIDUE ACT A 701 source : AC2 7) chain A residue 35 type sequence H description BINDING SITE FOR RESIDUE ACT A 701 source : AC2 8) chain A residue 50 type sequence W description BINDING SITE FOR RESIDUE ACT A 701 source : AC2 9) chain A residue 99 type sequence S description BINDING SITE FOR RESIDUE ACT A 701 source : AC2 10) chain B residue 94 type sequence Y description BINDING SITE FOR RESIDUE ACT A 701 source : AC2 11) chain L residue 192-198 type prosite sequence YACEVTH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH source prosite : PS00290 12) chain H residue 197-203 type prosite sequence YICNVNH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH source prosite : PS00290

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