eF-site ID 3gz3-B PDB Code 3gz3 Chain B click to enlarge Title Leishmania major Dihydroorotate Dehydrogenase in complex with orotate Classification OXIDOREDUCTASE Compound Dihydroorotate dehydrogenase, putative Source Leishmania major (Q4QEW7_LEIMA) Sequence B:  MSLQVNLLNNTFANPFMNAAGVMCTTTEELVAMTESASGS LVSKSCTPALREGNPTPRYQALPLGSINSMGLPNNGFDFY LAYAAEQHDYGKKPLFLSMSGLSMRENVEMCKRLAAVATE KGVILELNLDFDAMRQCLTAVSEVYPHSFGVKMPPYFDFA HFDAAAEILNEFPKVQFITCINSIGNGLVIDAETESVVIK PKQGFGGLGGRYVLPTALANINAFYRRCPGKLIFGCGGVY TGEDAFLHVLAGASMVQVGTALQEEGPSIFERLTSELLGV MAKKRYQTLDEFRGKVRTL Description Functional site 1) chain B residue 227 type sequence L description BINDING SITE FOR RESIDUE GOL A 323 source : AC3 2) chain B residue 231 type sequence L description BINDING SITE FOR RESIDUE GOL A 323 source : AC3 3) chain B residue 19 type sequence A description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 4) chain B residue 20 type sequence A description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 5) chain B residue 21 type sequence G description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 6) chain B residue 44 type sequence K description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 7) chain B residue 45 type sequence S description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 8) chain B residue 59 type sequence Y description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 9) chain B residue 68 type sequence N description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 10) chain B residue 70 type sequence M description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 11) chain B residue 128 type sequence N description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 12) chain B residue 165 type sequence K description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 13) chain B residue 194 type sequence I description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 14) chain B residue 195 type sequence N description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 15) chain B residue 222 type sequence G description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 16) chain B residue 223 type sequence G description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 17) chain B residue 226 type sequence V description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 18) chain B residue 249 type sequence C description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 19) chain B residue 250 type sequence G description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 20) chain B residue 251 type sequence G description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 21) chain B residue 272 type sequence G description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 22) chain B residue 273 type sequence T description BINDING SITE FOR RESIDUE FMN B 321 source : AC5 23) chain B residue 44 type sequence K description BINDING SITE FOR RESIDUE ORO B 322 source : AC6 24) chain B residue 68 type sequence N description BINDING SITE FOR RESIDUE ORO B 322 source : AC6 25) chain B residue 70 type sequence M description BINDING SITE FOR RESIDUE ORO B 322 source : AC6 26) chain B residue 71 type sequence G description BINDING SITE FOR RESIDUE ORO B 322 source : AC6 27) chain B residue 72 type sequence L description BINDING SITE FOR RESIDUE ORO B 322 source : AC6 28) chain B residue 128 type sequence N description BINDING SITE FOR RESIDUE ORO B 322 source : AC6 29) chain B residue 195 type sequence N description BINDING SITE FOR RESIDUE ORO B 322 source : AC6 30) chain B residue 196 type sequence S description BINDING SITE FOR RESIDUE ORO B 322 source : AC6 31) chain B residue 203 type sequence I description BINDING SITE FOR RESIDUE GOL B 323 source : AC7 32) chain B residue 63 type sequence P description BINDING SITE FOR RESIDUE GOL B 324 source : AC8 33) chain B residue 224 type sequence R description BINDING SITE FOR RESIDUE GOL B 324 source : AC8 34) chain B residue 253 type sequence Y description BINDING SITE FOR RESIDUE GOL B 324 source : AC8

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