eF-site ID 3gv6-AB
PDB Code 3gv6
Chain A, B

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Title Crystal Structure of human chromobox homolog 6 (CBX6) with H3K9 peptide
Classification Transcription/DNA binding protein
Compound Chromobox protein homolog 6
Source Homo sapiens (Human) (Q92133_XENLA)
Sequence A:  ERVFAAESIIKRRIRKGRIEYLVKWKGWAIKYSTWEPEEN
ILDSRLIAAFEQKERE
B:  QTARXS
Description


Functional site

1) chain B
residue 5
type MOD_RES
sequence Q
description 5-glutamyl serotonin; alternate => ECO:0000250|UniProtKB:Q71DI3
source Swiss-Prot : SWS_FT_FI4

2) chain B
residue 6
type MOD_RES
sequence T
description Phosphothreonine; by PKC => ECO:0000250|UniProtKB:Q71DI3
source Swiss-Prot : SWS_FT_FI5

3) chain B
residue 8
type MOD_RES
sequence R
description Symmetric dimethylarginine; by PRMT5; alternate => ECO:0000250
source Swiss-Prot : SWS_FT_FI6

4) chain B
residue 9
type MOD_RES
sequence X
description N6-methyllysine; alternate => ECO:0000305|PubMed:12138181
source Swiss-Prot : SWS_FT_FI7

5) chain B
residue 10
type MOD_RES
sequence S
description Phosphoserine; alternate; by AURKB, AURKC, RPS6KA3, RPS6KA4 and RPS6KA5 => ECO:0000250|UniProtKB:Q71DI3
source Swiss-Prot : SWS_FT_FI8

6) chain A
residue 28-48
type prosite
sequence YLVKWKGWAIKYSTWEPEENI
description CHROMO_1 Chromo domain signature. YlVKWkGWaikys.TWEPeenI
source prosite : PS00598


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