|
|
eF-site ID
|
3giz-H |
|
PDB Code
|
3giz |
|
Chain
|
H |
|
click to enlarge
|
|
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Title
|
Crystal structure of the Fab fragment of anti-CD20 antibody Ofatumumab |
|
Classification
|
IMMUNE SYSTEM |
|
Compound
|
Fab fragment of anti-CD20 antibody Ofatumumab, light chain |
|
Source
|
(3GIZ) |
|
|
Sequence
|
H: |
EVQLVESGGGLVQPGRSLRLSCAASGFTFNDYAMHWVRQA
PGKGLEWVSTISWNSGSIGYADSVKGRFTISRDNAKKSLY
LQMNSLRAEDTALYYCAKDIQYGNYYYGMDVWGQGTTVTV
SSASTKGPSVFPLAPGGTAALGCLVKDYFPEPVTVSWNSG
ALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICN
VNHKPSNTKVDKKVEP
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
H |
| residue |
1 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR RESIDUE ZN L 213
|
| source |
: AC2
|
|
|
2)
|
chain |
H |
| residue |
173 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ZN L 213
|
| source |
: AC2
|
|
|
3)
|
chain |
H |
| residue |
203-209 |
| type |
prosite |
| sequence |
YICNVNH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
|
| source |
prosite : PS00290
|
|
|
|