eF-site ID 3geb-A PDB Code 3geb Chain A click to enlarge Title Crystal Structure of edeya2 Classification HYDROLASE Compound Eyes absent homolog 2 Source Homo sapiens (Human) (EYA2_HUMAN) Sequence A:  SHMERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRI GLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQD LSTYNFSADGFGGVDWMRKLAFRYRRVKEMYNTYKNNVGG LIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPN CVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGK ESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRI SCHADLEALRHALELEYL Description Functional site 1) chain A residue 274 type sequence D description BINDING SITE FOR RESIDUE MG A 701 source : AC1 2) chain A residue 276 type sequence D description BINDING SITE FOR RESIDUE MG A 701 source : AC1 3) chain A residue 502 type sequence D description BINDING SITE FOR RESIDUE MG A 701 source : AC1 4) chain A residue 274 type BINDING sequence D description BINDING => ECO:0000269|PubMed:19351884 source Swiss-Prot : SWS_FT_FI3 5) chain A residue 276 type BINDING sequence D description BINDING => ECO:0000269|PubMed:19351884 source Swiss-Prot : SWS_FT_FI3 6) chain A residue 502 type BINDING sequence D description BINDING => ECO:0000269|PubMed:19351884 source Swiss-Prot : SWS_FT_FI3 7) chain A residue 274 type ACT_SITE sequence D description Nucleophile => ECO:0000269|PubMed:19858093 source Swiss-Prot : SWS_FT_FI1 8) chain A residue 276 type ACT_SITE sequence D description Proton donor => ECO:0000269|PubMed:19858093 source Swiss-Prot : SWS_FT_FI2

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