eF-site ID 3gdg-B PDB Code 3gdg Chain B click to enlarge Title Crystal structure of the NADP-dependent mannitol dehydrogenase from Cladosporium herbarum. Classification OXIDOREDUCTASE Compound Probable NADP-dependent mannitol dehydrogenase Source Davidiella tassiana (Mycosphaerella tassiana) (Cladosporium herbarum) (MTDH_CLAHE) Sequence B:  MPGQQATKHESLLDQLSLKGKVVVVTGASGPKGMGIEAAR GCAEMGAAVAITYASRAQGAEENVKELEKTYGIKAKAYKC QVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILDG SVEAWNHVVQVDLNGTFHCAKAVGHHFKERGTGSLVITAS MSGHIANFPQEQTSYNVAKAGCIHMARSLANEWRDFARVN SISPGYIDTGLSDFVPKETQQLWHSMIPMGRDGLAKELKG AYVYFASDASTYTTGADLLIDGGYTTR Description Functional site 1) chain B residue 267 type sequence R description BINDING SITE FOR RESIDUE NA B 1001 source : AC2 2) chain B residue 160 type ACT_SITE sequence S description Proton donor => ECO:0000305|PubMed:20420880 source Swiss-Prot : SWS_FT_FI1 3) chain B residue 175 type ACT_SITE sequence Y description Proton donor => ECO:0000305|PubMed:20420880 source Swiss-Prot : SWS_FT_FI1 4) chain B residue 179 type ACT_SITE sequence K description Lowers pKa of active site Tyr => ECO:0000305|PubMed:20420880 source Swiss-Prot : SWS_FT_FI2 5) chain B residue 108 type BINDING sequence N description BINDING => ECO:0000250|UniProtKB:O93868 source Swiss-Prot : SWS_FT_FI3 6) chain B residue 175 type BINDING sequence Y description BINDING => ECO:0000250|UniProtKB:O93868 source Swiss-Prot : SWS_FT_FI3 7) chain B residue 179 type BINDING sequence K description BINDING => ECO:0000250|UniProtKB:O93868 source Swiss-Prot : SWS_FT_FI3 8) chain B residue 207 type BINDING sequence I description BINDING => ECO:0000250|UniProtKB:O93868 source Swiss-Prot : SWS_FT_FI3 9) chain B residue 141 type BINDING sequence K description BINDING => ECO:0000250|UniProtKB:L0E2Z4 source Swiss-Prot : SWS_FT_FI4 10) chain B residue 209 type BINDING sequence T description BINDING => ECO:0000250|UniProtKB:L0E2Z4 source Swiss-Prot : SWS_FT_FI4

Display surface Download Links