eF-site ID 3gb8-AB PDB Code 3gb8 Chain A, B click to enlarge Title Crystal structure of CRM1/Snurportin-1 complex Classification TRANSPORT PROTEIN Compound Exportin-1 Source null (SPN1_HUMAN) Sequence A:  LKEHPRVDTILEFSQNMNTKYYGLQILENVIKTRWRNQCE GIKKYVVGLIIKTSSEKEKVYIGKLNMILVQILKQEWPKH WPTFISDIVGASRTSESLCQNNMVILKLLSEEVFTQVKSK HLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRF LNWIPLGYIFETKLISTLIYKFLNVPMFRNVSLKCLTEIA GVSVSQYEEQFVTLFTLTMMQLKQMLPLNTNIRLAYSNGK DDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALH YMLLVSEVEETEIFKICLEYWNHLAAELYRESPFSVPPRR QLYLPMLFKVRLLMVSRMAKPEEDTDSINLYKNMRETLVY LTHLDYVDTERIMTEKLHNQVNGTEWSWKNLNTLCWAIGS ISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAIIASN IMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDM ACDTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIIC DLQPQQVHTFYEAVGYMIGAQTDQTVQEHLIEKYMLLPNQ VWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVG HPFVIQLGRIYLDMLNVYKCLSENISAAIQANGEMVTKQP LIRSMRTVKRETLKLISGWVSRSNDPQMVAENFVPPLLDA VLIDYQRNVPAAREPEVLSTMAIIVNKLGGHITAEIPQIF DAVFECTLNMINKDFEEYPEHRTNFFLLLQAVNSHCFPAF LAIPPTQFKLVLDSIIWAFKHTMRNVADTGLQILFTLLQN VAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHA SILAYMFNLVEEGKISTSLNPGNPVNNQIFLQEYVANLLK SAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLVQIK EFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNP B:  SMEELSQALASSFSVSQDLNSTAAPHPRLSQYKSKYSSLE QSERRRRLLELQKSKRLDYVNHARRLALPKHYANQLMLSE WLIDVPSDLGQEWIVVVCPVGKRALIVASRGSTSAYTKSG YCVNRFSSLLPGGNRRNSTAKDYTILDCIYNEVNQTYYVL DVMCWRGHPFYDCQTDFRFYWMHSKLPEEEGLGEKTKLNP FKFVGLKNFPCTPESLCDVLSMDFPFEVDGLLFYHKQTHY SPGSTPLVGWLRPYMVSDVLGVAVPAGP Description Functional site 1) chain A residue 454 type MOD_RES sequence Y description Phosphotyrosine => ECO:0000250|UniProtKB:Q80U96 source Swiss-Prot : SWS_FT_FI5 2) chain A residue 1031 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI6 3) chain B residue 105 type SITE sequence S description Interaction with m3G-cap structure => ECO:0000269|PubMed:15920472, ECO:0007744|PDB:1XK5 source Swiss-Prot : SWS_FT_FI1 4) chain B residue 144 type SITE sequence K description Interaction with m3G-cap structure => ECO:0000269|PubMed:15920472, ECO:0007744|PDB:1XK5 source Swiss-Prot : SWS_FT_FI1 5) chain B residue 276 type SITE sequence W description Interaction with m3G-cap structure => ECO:0000269|PubMed:15920472, ECO:0007744|PDB:1XK5 source Swiss-Prot : SWS_FT_FI1 6) chain B residue 1 type MOD_RES sequence M description N-acetylmethionine => ECO:0007744|PubMed:20068231 source Swiss-Prot : SWS_FT_FI2 7) chain A residue 693 type MOD_RES sequence K description N-acetylmethionine => ECO:0007744|PubMed:20068231 source Swiss-Prot : SWS_FT_FI2 8) chain A residue 450 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:Q80U96 source Swiss-Prot : SWS_FT_FI4

Display surface Download Links