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eF-site ID
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3g6j-C |
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PDB Code
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3g6j |
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Chain
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C |
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click to enlarge
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Title
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C3b in complex with a C3b specific Fab |
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Classification
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IMMUNE SYSTEM |
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Compound
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Complement C3 beta chain |
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Source
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ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens; |
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Sequence
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C: |
SPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDF
PGKKLVLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGR
NKFVTVQATFGTQVVEKVVLVSLQSGYLFIQTDKTIYTPG
STVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSS
QNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEF
EVKEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYG
KKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEVVL
SRKVLLDGVQNPRAEDLVGKSLYVSATVILHSGSDMVQAE
RSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGS
PAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPLSI
TVRTKKQELSEAEQATRTMQALPYSTVGNSNNYLHLSVLR
TELRPGETLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLK
AGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASG
QREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMT
LKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEK
ADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQC
PQ
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Description
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Functional site
|
|
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1)
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chain |
C |
| residue |
505 |
| type |
|
| sequence |
P
|
| description |
BINDING SITE FOR RESIDUE CA C 645
|
| source |
: AC2
|
|
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2)
|
chain |
C |
| residue |
532 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE CA C 645
|
| source |
: AC2
|
|
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3)
|
chain |
C |
| residue |
533 |
| type |
|
| sequence |
V
|
| description |
BINDING SITE FOR RESIDUE CA C 645
|
| source |
: AC2
|
|
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4)
|
chain |
C |
| residue |
535 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE CA C 645
|
| source |
: AC2
|
|
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5)
|
chain |
C |
| residue |
16 |
| type |
SITE |
| sequence |
S
|
| description |
Cleavage; by factor I
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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6)
|
chain |
C |
| residue |
48 |
| type |
SITE |
| sequence |
S
|
| description |
Cleavage; by factor I
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
7)
|
chain |
C |
| residue |
275 |
| type |
SITE |
| sequence |
S
|
| description |
Cleavage; by factor I
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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8)
|
chain |
C |
| residue |
281 |
| type |
SITE |
| sequence |
S
|
| description |
Cleavage; by factor I
|
| source |
Swiss-Prot : SWS_FT_FI2
|
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