eF-site ID 3fkz-A
PDB Code 3fkz
Chain A

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Title X-ray structure of the non covalent swapped form of the S16G/T17N/A19P/A20S/K31C/S32C mutant of bovine pancreatic ribonuclease
Classification HYDROLASE
Compound Ribonuclease pancreatic
Source Bos taurus (Bovine) (RNAS1_BOVIN)
Sequence A:  KETAAAKFERQHMDSGNSPSSSSNYCNQMMXXRNLTKDRC
KPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMS
ITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHF
DASV
Description


Functional site

1) chain A
residue 12
type catalytic
sequence H
description 164
source MCSA : MCSA1

2) chain A
residue 41
type catalytic
sequence K
description 164
source MCSA : MCSA1

3) chain A
residue 119
type catalytic
sequence H
description 164
source MCSA : MCSA1

4) chain A
residue 120
type catalytic
sequence F
description 164
source MCSA : MCSA1

5) chain A
residue 121
type catalytic
sequence D
description 164
source MCSA : MCSA1

6) chain A
residue 1
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:4030761
source Swiss-Prot : SWS_FT_FI4

7) chain A
residue 7
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:4030761
source Swiss-Prot : SWS_FT_FI4

8) chain A
residue 37
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:4030761
source Swiss-Prot : SWS_FT_FI4

9) chain A
residue 41
type CARBOHYD
sequence K
description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:4030761
source Swiss-Prot : SWS_FT_FI4

10) chain A
residue 7
type BINDING
sequence K
description
source Swiss-Prot : SWS_FT_FI3

11) chain A
residue 10
type BINDING
sequence R
description
source Swiss-Prot : SWS_FT_FI3

12) chain A
residue 41
type BINDING
sequence K
description
source Swiss-Prot : SWS_FT_FI3

13) chain A
residue 66
type BINDING
sequence K
description
source Swiss-Prot : SWS_FT_FI3

14) chain A
residue 85
type BINDING
sequence R
description
source Swiss-Prot : SWS_FT_FI3

15) chain A
residue 12
type ACT_SITE
sequence H
description Proton acceptor
source Swiss-Prot : SWS_FT_FI1

16) chain A
residue 119
type ACT_SITE
sequence H
description Proton donor
source Swiss-Prot : SWS_FT_FI2

17) chain A
residue 40-46
type prosite
sequence CKPVNTF
description RNASE_PANCREATIC Pancreatic ribonuclease family signature. CKpvNTF
source prosite : PS00127

18) chain A
residue 34
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine; partial => ECO:0000269|PubMed:19358553
source Swiss-Prot : SWS_FT_FI5


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