eF-site ID 3fk2-ABCD PDB Code 3fk2 Chain A, B, C, D click to enlarge Title Crystal structure of the RhoGAP domain of human glucocorticoid receptor DNA-binding factor 1 Classification SIGNALING PROTEIN, HYDROLASE ACTIVATOR Compound Glucocorticoid receptor DNA-binding factor 1 Source Homo sapiens (Human) (GRLF1_HUMAN) Sequence A:  WESNYFGVPLTTVVTPEKPIPIFIERCIEYIEATGLSTEG IYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGAM KSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVL KKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFW PTLMRPDFSTMDALTATRTYQTIIELFIQQCPFFFY B:  WESNYFGVPLTTVVTPEKPIPIFIERCIEYIEATGLSTEG IYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGAM KSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVL KKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFW PTLMRPDMDALTATRTYQTIIELFIQQCPFFFY C:  SNYFGVPLTTVVTPEKPIPIFIERCIEYIEATGLSTEGIY RVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGAMKS FFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKK FPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPT LMRPDFSTMDALTATRTYQTIIELFIQQCPFFFYN D:  WESNYFGVPLTTVVTPEKPIPIFIERCIEYIEATGLSTEG IYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGAM KSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVL KKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFW PTLMRPDFSTMDALTATRTYQTIIELFIQQCPFFFY Description Functional site 1) chain A residue 1313 type sequence T description BINDING SITE FOR RESIDUE UNX A 1 source : AC1 2) chain B residue 1313 type sequence T description BINDING SITE FOR RESIDUE UNX B 2 source : AC2 3) chain C residue 1313 type sequence T description BINDING SITE FOR RESIDUE UNX C 3 source : AC3 4) chain D residue 1313 type sequence T description BINDING SITE FOR RESIDUE UNX D 4 source : AC4 5) chain A residue 1431 type sequence Q description BINDING SITE FOR RESIDUE UNX A 5 source : AC5 6) chain C residue 1430 type sequence Q description BINDING SITE FOR RESIDUE UNX A 5 source : AC5 7) chain C residue 1431 type sequence Q description BINDING SITE FOR RESIDUE UNX A 5 source : AC5 8) chain C residue 1433 type sequence P description BINDING SITE FOR RESIDUE UNX A 5 source : AC5 9) chain C residue 1434 type sequence F description BINDING SITE FOR RESIDUE UNX A 5 source : AC5 10) chain B residue 1431 type sequence Q description BINDING SITE FOR RESIDUE UNX B 6 source : AC6 11) chain D residue 1431 type sequence Q description BINDING SITE FOR RESIDUE UNX B 6 source : AC6 12) chain D residue 1433 type sequence P description BINDING SITE FOR RESIDUE UNX B 6 source : AC6 13) chain D residue 1434 type sequence F description BINDING SITE FOR RESIDUE UNX B 6 source : AC6 14) chain A residue 1431 type sequence Q description BINDING SITE FOR RESIDUE UNX C 7 source : AC7 15) chain A residue 1433 type sequence P description BINDING SITE FOR RESIDUE UNX C 7 source : AC7 16) chain A residue 1434 type sequence F description BINDING SITE FOR RESIDUE UNX C 7 source : AC7 17) chain C residue 1431 type sequence Q description BINDING SITE FOR RESIDUE UNX C 7 source : AC7 18) chain C residue 1434 type sequence F description BINDING SITE FOR RESIDUE UNX C 7 source : AC7 19) chain B residue 1431 type sequence Q description BINDING SITE FOR RESIDUE UNX D 8 source : AC8 20) chain B residue 1433 type sequence P description BINDING SITE FOR RESIDUE UNX D 8 source : AC8 21) chain B residue 1434 type sequence F description BINDING SITE FOR RESIDUE UNX D 8 source : AC8 22) chain D residue 1431 type sequence Q description BINDING SITE FOR RESIDUE UNX D 8 source : AC8

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