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|
eF-site ID
|
3fib-A |
|
PDB Code
|
3fib |
|
Chain
|
A |
|
click to enlarge
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Title
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RECOMBINANT HUMAN GAMMA-FIBRINOGEN CARBOXYL TERMINAL FRAGMENT (RESIDUES 143-411) BOUND TO CALCIUM AT PH 6.0: A FURTHER REFINEMENT OF PDB ENTRY 1FIB, AND DIFFERS FROM 1FIB BY THE MODELLING OF A CIS PEPTIDE BOND BETWEEN RESIDUES K338 AND C339 |
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Classification
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BLOOD COAGULATION |
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Compound
|
FIBRINOGEN GAMMA CHAIN RESIDUES |
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Source
|
null (FIBG_HUMAN) |
|
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Sequence
|
A: |
QIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCE
IDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGT
TEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYA
MFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKF
FTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGH
LNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTT
MKIIPFNRL
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Description
|
(1) |
FIBRINOGEN GAMMA CHAIN RESIDUES
|
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Functional site
|
|
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1)
|
chain |
A |
| residue |
318 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE CA A 400
|
| source |
: AC1
|
|
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2)
|
chain |
A |
| residue |
320 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE CA A 400
|
| source |
: AC1
|
|
|
3)
|
chain |
A |
| residue |
322 |
| type |
|
| sequence |
F
|
| description |
BINDING SITE FOR RESIDUE CA A 400
|
| source |
: AC1
|
|
|
4)
|
chain |
A |
| residue |
324 |
| type |
|
| sequence |
G
|
| description |
BINDING SITE FOR RESIDUE CA A 400
|
| source |
: AC1
|
|
|
5)
|
chain |
A |
| residue |
322 |
| type |
BINDING |
| sequence |
F
|
| description |
BINDING => ECO:0000269|PubMed:10074346, ECO:0000269|PubMed:19296670, ECO:0000269|PubMed:9016719, ECO:0000269|PubMed:9207064, ECO:0000269|PubMed:9333233, ECO:0000269|PubMed:9628725, ECO:0007744|PDB:1FID
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
A |
| residue |
324 |
| type |
BINDING |
| sequence |
G
|
| description |
BINDING => ECO:0000269|PubMed:10074346, ECO:0000269|PubMed:19296670, ECO:0000269|PubMed:9016719, ECO:0000269|PubMed:9207064, ECO:0000269|PubMed:9333233, ECO:0000269|PubMed:9628725, ECO:0007744|PDB:1FID
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
7)
|
chain |
A |
| residue |
318 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:10074346, ECO:0000269|PubMed:19296670, ECO:0000269|PubMed:9016719, ECO:0000269|PubMed:9207064, ECO:0000269|PubMed:9333233, ECO:0000269|PubMed:9628725, ECO:0007744|PDB:1FID
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
8)
|
chain |
A |
| residue |
320 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:10074346, ECO:0000269|PubMed:19296670, ECO:0000269|PubMed:9016719, ECO:0000269|PubMed:9207064, ECO:0000269|PubMed:9333233, ECO:0000269|PubMed:9628725, ECO:0007744|PDB:1FID
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
9)
|
chain |
A |
| residue |
308 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine; in variant Asahi
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
10)
|
chain |
A |
| residue |
334-346 |
| type |
prosite |
| sequence |
WWMNKCHAGHLNG
|
| description |
FIBRINOGEN_C_1 Fibrinogen C-terminal domain signature. WWMnkChaGhlNG
|
| source |
prosite : PS00514
|
|
|
|