eF-site ID 3ffq-AB PDB Code 3ffq Chain A, B click to enlarge Title HCN2I 443-640 apo-state Classification METAL TRANSPORT Compound Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 Source null (HCN2_MOUSE) Sequence A:  SRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGK MFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPN FVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSV LTNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSL SVDNFNEVLEEYPMMRRAFETVAI B:  DSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQ GKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANAD PNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVV SVLTKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYS LSVDNFNEVLEEYPMMRRAFETVA Description Functional site 1) chain A residue 584 type sequence C description BINDING SITE FOR RESIDUE BR A 1 source : AC1 2) chain A residue 479 type sequence H description BINDING SITE FOR RESIDUE BR A 3 source : AC3 3) chain A residue 600 type sequence Y description BINDING SITE FOR RESIDUE BR A 3 source : AC3 4) chain A residue 618 type sequence Y description BINDING SITE FOR RESIDUE BR A 4 source : AC4 5) chain A residue 620 type sequence M description BINDING SITE FOR RESIDUE BR A 4 source : AC4 6) chain A residue 599 type sequence T description BINDING SITE FOR RESIDUE BR A 5 source : AC5 7) chain A residue 600 type sequence Y description BINDING SITE FOR RESIDUE BR A 5 source : AC5 8) chain B residue 599 type sequence T description BINDING SITE FOR RESIDUE BR A 5 source : AC5 9) chain B residue 600 type sequence Y description BINDING SITE FOR RESIDUE BR A 5 source : AC5 10) chain B residue 479 type sequence H description BINDING SITE FOR RESIDUE BR B 1 source : AC6 11) chain B residue 600 type sequence Y description BINDING SITE FOR RESIDUE BR B 1 source : AC6 12) chain B residue 584 type sequence C description BINDING SITE FOR RESIDUE BR B 2 source : AC7 13) chain B residue 580 type sequence F description BINDING SITE FOR RESIDUE BR B 3 source : AC8 14) chain B residue 618 type sequence Y description BINDING SITE FOR RESIDUE BR B 4 source : AC9 15) chain B residue 619 type sequence P description BINDING SITE FOR RESIDUE BR B 4 source : AC9 16) chain B residue 620 type sequence M description BINDING SITE FOR RESIDUE BR B 4 source : AC9 17) chain A residue 581 type BINDING sequence G description BINDING => ECO:0000269|PubMed:18367452, ECO:0000269|PubMed:19525958 source Swiss-Prot : SWS_FT_FI1 18) chain A residue 591 type BINDING sequence R description BINDING => ECO:0000269|PubMed:18367452, ECO:0000269|PubMed:19525958 source Swiss-Prot : SWS_FT_FI1 19) chain B residue 581 type BINDING sequence G description BINDING => ECO:0000269|PubMed:18367452, ECO:0000269|PubMed:19525958 source Swiss-Prot : SWS_FT_FI1 20) chain B residue 591 type BINDING sequence R description BINDING => ECO:0000269|PubMed:18367452, ECO:0000269|PubMed:19525958 source Swiss-Prot : SWS_FT_FI1 21) chain A residue 544-560 type prosite sequence IIREGTIGKKMYFIQHG description CNMP_BINDING_1 Cyclic nucleotide-binding domain signature 1. IIrEGTiGKkMYFIqhG source prosite : PS00888

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